25N-NBOMe

Since 1 January 2012, 25N-NBOMe has been structurally covered by the generic phenethylamine definition in Anlage II Z 2 of the Neue-Psychoaktive-Substanzen-Verordnung, rather than being expressly named. Under § 4 of the Neue-Psychoaktive-Substanzen-Gesetz, production, import, export, supply, and procuring the substance for another person are punishable when undertaken with intent to obtain an advantage and with intent that another person or a third party use the substance to achieve a psychoactive effect. The basic offence carries up to two years' imprisonment, and the penalty is one to ten years if the offence causes a person's death or serious bodily injury to a larger number of people. Simple possession for personal use is not a standalone offence under § 4, but § 5 permits confiscation unless lawful use and safeguards against psychoactive use are established.

25N-NBOMe is listed by exact name in Lista F2 of Anexo I to Portaria SVS/MS nº 344, de 12 de maio de 1998. The listing began on 19 February 2014; the current Annex I was republished by Resolução da Diretoria Colegiada Anvisa nº 1.036, de 9 de julho de 2026, effective 13 July 2026. Article 4 prohibits production, manufacture, import, export, commerce, and use of proscribed substances, subject to authorization for medical and scientific research. Article 4-A also permits establishments duly authorized by Anvisa to stock controlled analytical standards for distribution to establishments conducting laboratory analysis, teaching, and research activities, provided the stock is compatible with the company's routine. Lista F2 adendo 16 waives only the Import Authorization and Export Authorization requirements for analytical standards based on 25N-NBOMe when the controlled active ingredient does not exceed 500 mg per unit; this limited exception extends to standards based on its salts and isomers unless expressly excepted or subject to stricter control. For personal use, article 28 of Lei nº 11.343/2006 covers acquiring, keeping, holding in storage, transporting, or carrying it without authorization or contrary to law or regulation.

25N-NBOMe (2C-N-NBOMe) is listed in Anlage I of the Betäubungsmittelgesetz as a non-marketable narcotic drug. The listing took effect on 9 June 2016. Under § 29(1), unauthorized production, trade, import, export, sale, supply, acquisition or procurement, and possession without written acquisition authorization are punishable by imprisonment for up to five years or a fine.

Since 1 June 2021, 25N-NBOMe has been covered by the Schedule I generic class for 2,5-dimethoxyphenethylamines in Par Krimināllikuma spēkā stāšanās un piemērošanas kārtību, 2. pielikuma II nodaļas 11. punkta 1. apakšpunkts, rather than being individually named. The controlled conduct includes cultivation, production, manufacture, import, export, distribution, advertising, transport, storage, transfer, acquisition, use, and transit. For this class, up to 0.02 g is treated as a small amount and 2 g or more as a large amount. Authorized Schedule I activity is permitted for medical or veterinary scientific research, determination of physical and chemical properties, and training.

25N-NBOMe, identified as 2-(2,5-dimetoxi-4-nitrofenyl)-N-(2-metoxibensyl)etanamin, is expressly named in Annex 1 to Förordning (1992:1554) om kontroll av narkotika and listed in Förteckning I of Läkemedelsverkets föreskrifter (LVFS 2011:10) om förteckningar över narkotika. The Government added it to Annex 1 through SFS 2014:1480, while Läkemedelsverket added it to Förteckning I through LVFS 2014:11; both measures took effect on 16 January 2015. Förteckning I covers substances, plant materials, and fungi that normally have no medical use. Under Narkotikastrafflag (1968:64), unauthorized transfer, production for abuse, acquisition for transfer, procurement, processing, packaging, transport, storage, possession, use, sale, and offering for sale are prohibited. Separately authorized medical, scientific, especially important public-interest, and industrial channels remain available.

The current Betäubungsmittelverzeichnisverordnung (BetmVV-EDI) expressly lists 25N-NBOMe in Annex 6, Verzeichnis e, together with the chemical names 2,5-dimethoxy-4-nitro-N-(2-methoxybenzyl)phenethylamine and 2-(2,5-dimethoxyphenyl-4-nitro)-N-(2-methoxybenzyl)ethylamine. Verzeichnis e materials and products are subject to the control measures applicable to Verzeichnis a narcotics. Cultivation, manufacture, import, export, storage, use or placing on the market requires authorization from the Federal Department of Home Affairs; unauthorized conduct is punishable by imprisonment for up to three years or a monetary penalty.

25N-NBOMe is covered by the generic structural definition in Part I, paragraph 1(f), of Schedule 2 to the Misuse of Drugs Act 1971 and is therefore a Class A controlled drug. The provision was inserted by the Misuse of Drugs Act 1971 (Ketamine etc.) (Amendment) Order 2014 and took effect on 10 June 2014. Subject to licensing, regulatory, and statutory exceptions, the Act prohibits its possession, production, supply, offering to supply, import, and export.