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25H-NBOMe

This article is a stubmissing:
Subjective Effects
Pharmacology
Tolerance
History & Culture
25H-NBOMe molecule structure25H-NBOMe molecule structure
2-(2,5-Dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine
2C-H-NBOMe, NBOMe-2C-H
Psychoactive Class

Dosage & Duration

Duration

Onset30-90 minutes
After Effects2-3 hours
Total3-5 hours

Subjective Effects

Subjective Effects not written up yet

Reagent Testing

Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.

Marquis(MQ)
white → brown1 → brown2
Mecke(ME)
white → yellow2 → green2 → black3
Mandelin(MD)
yellow2 → green3 → orange3 → black3
Liebermann(LB)
white → yellow2 → black3
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Pharmacology

Pharmacology not written up yet

Interactions

Dangerous

Highest risk

These combinations are considered extremely harmful and should always be avoided. Reactions to these drugs taken in combination are highly unpredictable and have a potential to cause death.

Unsafe

Avoid

There is considerable risk of physical harm when taking these combinations, they should be avoided where possible.

AmphetaminesCocaineDXMTramadol

Caution

Use caution

These combinations are not usually physically harmful, but may produce undesirable effects, such as physical discomfort or overstimulation. Extreme use may cause physical health issues. Synergistic effects may be unpredictable. Care should be taken when choosing to use this combination.

2C-T-x compounds2C-x compounds5-MeO-xxT tryptaminesCaffeineCannabisDiphenhydramineDOx compoundsMAOIsMDMAMescalineMXE
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Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

Low

Has shown reinforcing effects in rodent studies, including conditioned place preference and self-administration, suggesting some potential for psychological reinforcement.

Toxicity

Cardiovascular

Suspected vasoconstrictive properties may pose risks at high doses; the extent of cardiovascular danger in humans remains poorly characterized.

History & Culture

History & Culture not written up yet

Legality

By Country

Illegal2
Sweden flagSwedenIllegal
United Kingdom flagUnited KingdomIllegal

References

Source Pages

  1. PsychonautWiki Talk: 25H-NBOMe
  2. PsychonautWiki: 25x-NBOMe series
  3. The Small & Handy 25H-NBOMe Thread - Bluelight user reports
  4. TripSit: Factsheet - 25H-NBOMe
  5. Wikipedia

Citations

  1. Läkemedelsverkets föreskrifter (LVFS 2011:10) om förteckningar över narkotika (konsoliderad genom HSLF-FS 2026:26). lakemedelsverket.se (n.d.). https://www.lakemedelsverket.se/globalassets/dokument/lagar-och-regler/lvfs/lvfs-2011-10-konsoliderad.pdf1
  2. Föreskrifter (LVFS 2013:15) om ändring i Läkemedelsverkets föreskrifter (LVFS 2011:10) om förteckningar över narkotika. lakemedelsverket.se (n.d.). https://www.lakemedelsverket.se/globalassets/dokument/lagar-och-regler/lvfs/lvfs-2013-15.pdf1
  3. Förordning (1992:1554) om kontroll av narkotika. data.riksdagen.se (n.d.). https://data.riksdagen.se/dokument/sfs-1992-1554.html1
  4. Förordning (2013:640) om ändring i förordningen (1992:1554) om kontroll av narkotika. rkrattsdb.gov.se (n.d.). https://rkrattsdb.gov.se/SFSdoc/13/130640.PDF1
  5. Narkotikastrafflag (1968:64). data.riksdagen.se (n.d.). https://data.riksdagen.se/dokument/sfs-1968-64.html1
  6. PubChem CID 39424372 Synonyms. pubchem.ncbi.nlm.nih.gov (n.d.). https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/39424372/synonyms/JSON1
  7. PubChem CID 39424372 Chemical Properties. pubchem.ncbi.nlm.nih.gov (n.d.). https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/39424372/property/IUPACName,CanonicalSMILES,IsomericSMILES,MolecularFormula/JSON1
  8. Misuse of Drugs Act 1971, Schedule 2 Part I paragraph 1(c). legislation.gov.uk (n.d.). https://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I/paragraph/11
  9. Misuse of Drugs Act 1971, section 5. legislation.gov.uk (n.d.). https://www.legislation.gov.uk/ukpga/1971/38/section/51
  10. The Misuse of Drugs Act 1971 (Ketamine etc.) (Amendment) Order 2014, article 1. legislation.gov.uk (n.d.). https://www.legislation.gov.uk/uksi/2014/1106/article/1/made1

Further Reading

  1. Braden MR et al. (2006) N-benzyl phenethylamines as potent 5-HT2A receptor agonists
  2. Johnson RD et al. (2014) LC-MS-MS evaluation of NBOMe compounds
  3. Poklis JL et al. (2014) NBOMe intoxication case report with 25B-NBOMe quantification
  4. Pottie E et al. (2021) Serotonin 2A receptor activation by 25H-NBOMe positional isomers
  5. Suzuki J et al. (2015) Toxicities associated with NBOMe ingestion: systematic review
  6. Zawilska JB & Kacela M (2020) NBOMes - Highly potent and toxic alternatives of LSD

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

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    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

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24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

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