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2C-T-7
2,5-Dimethoxy-4-propylthiophenethylamine
Blue Mystic, Beautiful, 7th Heaven, T7
2C-T-7 is a 2C-x substituted phenethylamine psychedelic with both psychedelic and entactogenic properties. Alexander Shulgin developed it, later included it in PiHKAL, and it appeared in the scientific literature around 1990. He counted it among his "magical half-dozen" - the phenethylamines he regarded as most significant. The compound is especially sensitive to dose, and users often describe prominent visuals alongside a heavy somatic load.
Dosage & Duration
Dosage
Doses are population estimates that vary widely between individuals.
Threshold~3 mg
Light3-15 mg
Moderate15-25 mg
Strong25-40 mg
Heavy40+ mg
Duration
Onset60-90 minutes
Come Up10-30 minutes
Peak3-5 hours
Offset1-3 hours
After Effects2-8 hours
Total6-10 hours
Subjective Effects
Legacy content. A statistically backed ontology from Mindstate Design Labs is coming soon.
Effects vary widely by individual, dose, and context.
Physical
Cognitive
The head space of 2C-T-7 is described by many as one which is both insightful and relatively normal in its thought processes even at moderate to high dosages.
Visual
Geometry
The visual geometry of 2C-T-7 can be described as more similar in appearance to that of 4-AcO-DMT or ayahuasca than that of LSD, 2C-B or 2C-I. They can be comprehensively described as structured in their organization, organic in geometric style, intricate in complexity, large in size, fast and smooth in motion, colourful in scheme, glossy in colour, sharp in their edges and equally rounded and angular in their corners. They give off a contradictory natural and synthetic feel with slightly more mystical and shamanic undertones to them in comparison to other phenethylamines. At higher dosages they are equally likely to result in states of Level 7A visual geometry and Level 7B. The visual geometry is extremely similar to 2C-E and 2C-P and can be described as equal in intensity or complexity.
Hallucinatory States
2C-T-7 produces a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of many other commonly used psychedelics, particularly in comparison to other substances within the phenethylamine family.
Auditory
The auditory effects of 2C-T-7 are more common in their occurrence than many more commonly used psychedelics.
See also: Psychedelic Intensity Scale, Effects of psychedelics (visual, cognitive, miscellaneous)
Pharmacology
Pharmacodynamics
2C-T-7 acts as a partial agonist at the serotonin 5-HT2A receptor, which is considered the primary mechanism responsible for its psychedelic effects.citation needed The 2,5-desmethoxy derivative of 2C-T-7 has been shown to be a moderate monoamine oxidase A (MAO-A) inhibitor, and 2C-T-7 itself is widely thought to possess some degree of MAO-A inhibitory activity as well, though this has not been directly confirmed for the parent compound.
Pharmacokinetics
In rat urine, 2C-T-7 metabolites indicated propyl-side-chain hydroxylation followed by N-acetylation and sulfoxidation, as well as deamination followed by oxidation to an acid or reduction to an alcohol. Minor pathways included S-dealkylation, N-acetylation, S-methylation, and sulfoxidation.1 In experiments with cDNA-expressed human enzymes, MAO-A and MAO-B were the principal enzymes responsible for 2C-T-7 deamination; CYP2D6 contributed only to a very small extent.2 These studies do not establish oral or intranasal bioavailability, an elimination half-life, or other whole-body pharmacokinetic parameters in humans.12
Metabolitesnone documented yet
Dangerous
Highest riskThese combinations are considered extremely harmful and should always be avoided. Reactions to these drugs taken in combination are highly unpredictable and have a potential to cause death.
Unsafe
AvoidThere is considerable risk of physical harm when taking these combinations, they should be avoided where possible.
Caution
Use cautionThese combinations are not usually physically harmful, but may produce undesirable effects, such as physical discomfort or overstimulation. Extreme use may cause physical health issues. Synergistic effects may be unpredictable. Care should be taken when choosing to use this combination.
Tolerance
Tolerance timelines are rules of thumb, not exact schedules, and vary widely between individuals and use patterns.
Full Tolerance
2C-T-7 can produce tolerance almost immediately after use. Daily consecutive use substantially reduces effects, and users often need about twice as much on later days for comparable results.
Baseline Reset
5-7 days for most users, though full baseline restoration is typically achieved within 7 days of abstinence.
Half Tolerance
Approximately 3 days
Cross Tolerance
Serotonergic psychedelics
Harm Potential
Addiction & Dependence
Psychological
Extremely Low2C-T-7 is not habit-forming and is unlikely to cause psychological dependence. The desire to use it often decreases with repeated use, and it is described as self-regulating by most users.
Physical
Extremely Low2C-T-7 is not physically addicting. Withdrawal effects following discontinuation have not been reported.
Toxicity
Nasal Mucosa
Insufflation of 2C-T-7 causes intense burning pain lasting 5-15 minutes, leaves an unpleasant drip, and can lead to sinus and throat infections with repeated use; oral administration does not carry this risk.
Psychosis Risk
At high doses, 2C-T-7 can produce severe dissociation and deliriumcitation needed characterized by complete disorientation, memory loss, confusion about having ingested a substance, and in some cases belligerent or violent behavior. These effects are dose-dependent and primarily associated with doses exceeding typical recreational ranges, particularly via insufflation. At typical oral doses, the headspace is described as relatively clear and insightful. Individuals with a family history of schizophrenia or early onset mental illness are advised to exercise extreme caution as psychedelics may trigger latent psychological conditions.
Seizure Risk
Muscle tremors and convulsions are listed among possible negative effects.citation needed Individuals with pre-existing seizure or convulsive disorders are warned they may be at elevated risk when using this substance.
History & Culture
Discovery and Development
2C-T-7 was developed around 1980 by Alexander Shulgin and Peyton Jacob III as part of Shulgin's extensive research program into substituted phenethylamines. The compound was first described in scientific literature by Myron Stolaroff by 1990, with more detailed characterization published by Shulgin…
Trip Reports
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Legality
International
2C-T-7 is not listed under the 1961 Single Convention on Narcotic Drugs. It is listed in Schedule II of the 1971 Convention on Psychotropic Substances. It is not listed under the 1988 Convention against Illicit Traffic in Narcotic Drugs and Psychotropic Substances.
By Country
Illegal25
United StatesIllegalControlled Substances Act; DEA Final Rule, 69 FR 1279440
Classified as Schedule I by emergency DEA ruling on September 20, 2002.41 Permanently placed in Schedule I on March 18, 2004 when the DEA published a Final Rule in the Federal Register (69 FR 12794).42 Manufacturing, buying, possessing, or distributing without a DEA license is illegal.
By state
Across the 50 states, D.C., and the permanent territories, most jurisdictions treat 2C-T-7 consistently with federal control; listed entries record independently verified differences in state classification or coverage.
TexasIllegalTex. Health & Safety Code § 481.10343
Texas classifies 2C-T-7 as a Penalty Group 2 controlled substance rather than placing it in a state Schedule I. Manufacture, delivery, possession, and related conduct are prohibited and penalized under the Texas Controlled Substances Act's Penalty Group 2 provisions.
AustraliaIllegalTherapeutic Goods (Poisons Standard—February 2026) Instrument 20264
Covered by analogue drug laws and formally added to Schedule 9 (the most restrictive category) by the National Drugs and Poisons Schedule Committee in 2005.
AustriaIllegalSuchtgiftverordnung5
Prohibited under the Suchtmittelgesetz (SMG). Possession, production, and sale are illegal.
BrazilIllegalPortaria SVS/MS nº 344/1998, Lista F28
Possession, production, and sale are illegal. Listed on Portaria SVS/MS nº 344 as of February 18, 2014.
CanadaIllegal2C-T-7 is a Schedule III controlled substance under the Controlled Drugs and Substances Act because it falls within the Act's 2C-phenethylamine structural definition: a 1-amino-2-phenylethane with 2′ and 5′ alkoxy substitution and further benzene-ring substitution. The Schedule III entry has applied since October 31, 2016. Unauthorized possession, production, trafficking, importation, and exportation are prohibited, subject to authorization under the applicable regulations or an exemption under the Act.
Czech RepublicIllegal2C-T-7 is listed as Dimethoxypropylthiofenethylamin in List I of psychotropic substances under Government Regulation No. 463/2013 Coll. The Act on Addictive Substances treats the regulation's listed substances as addictive substances; handling includes research, manufacture, processing, acquisition, storage, supply, use, purchase and sale, and requires a Ministry of Health permit. Substances in Annex 4 may be used only for limited research, scientific, and very limited therapeutic purposes specified in that permit, so unpermitted possession, production, and sale are prohibited.
DenmarkIllegalBekendtgørelse om euforiserende stoffer16
Added to category B of the controlled substances list on August 23, 2003.
EstoniaIllegalNarkootiliste ja psühhotroopsete ainete nimekirjad ning nende ainete meditsiinilisel ja teaduslikul eesmärgil käitlemine17
Added to Schedule I in February 2011 alongside several other novel psychoactive substances.
FinlandIllegalValtioneuvoston asetus huumausaineina pidettävistä aineista, valmisteista ja kasveista 543/200818
Scheduled under the government decree on substances, preparations, and plants considered to be narcotic drugs.
ItalyIllegalDecreto del Ministero della salute 11 gennaio 200522
Added to Tabella I (list of prohibited plants and substances) by Ministry of Health statement on January 11, 2005.
LatviaIllegalMinistru kabineta noteikumi Nr. 84723
Classified as a Schedule I controlled substance. Possession, production, and distribution are prohibited.
NetherlandsIllegalOpiumwet24
The first country to ban 2C-T-7 after brief availability in smartshops. Following the ban on 2C-T-2, 2C-T-7 appeared on the market but was quickly prohibited under List I of the Opium Law.
NorwayIllegal2C-T-7 is listed in Norway’s Narkotikalisten to the Narkotikaforskriften under its chemical name, 2,5-dimetoksy-4-propyltiofenetylamin. The list marks it as prohibited under section 5 of the regulation. As a listed narcotic, unlawful possession and use are prohibited under the Medicines Act, and narcotic manufacture, import, trade, supply and dispatch are subject to the statutory narcotics controls.
PolandIllegalUstawa o przeciwdziałaniu narkomanii28
Reported as a Schedule I controlled substance. Possession, production, and distribution are prohibited.
PortugalIllegalDecreto-Lei n.º 15/93, Tabela II-A29
Legislation enacted in January 2005 to control 2C-T-7 alongside 2C-I, 2C-T-2, and TMA-2.
SpainIllegalOrden SCO/2359/2004, de 2 de julio, por la que se incluyen determinadas sustancias en la lista I del anexo I del Real Decreto 2829/1977, de 6 de octubre3233
2C-T-7 (2,5-dimetoxi-4-(n)-propiltiofenetilamina) is included in Lista I of Annex I to Real Decreto 2829/1977 by Orden SCO/2359/2004. Since 17 July 2004, its use, manufacture, importation, exportation, transit, trade, distribution, possession, and inclusion in any preparation are prohibited in Spain. Scientific research requires prior authorization from the Spanish Agency of Medicines and Medical Devices.
SwedenIllegalLäkemedelsverkets föreskrifter om förteckningar över narkotika, HSLF-FS 2019:134
First classified as a health hazard under the Act on the Prohibition of Certain Goods Dangerous to Health (SFS 1999:58) as of April 1, 1999, making it illegal to sell or possess. Subsequently added to Schedule I as of March 16, 2004.
UkraineIllegalCabinet of Ministers of Ukraine Resolution No. 770 of 6 May 2000, List of Narcotic Drugs, Psychotropic Substances and Precursors, as amended by Resolution No. 4 of 5 January 20113738
Ukraine lists 2C-T-7 (2,5-dimethoxy-4-N-propylthiophenethylamine) in List No. 2 of Table I of the national controlled-substances list. List No. 2 covers especially dangerous psychotropic substances whose circulation is prohibited; the substance has been listed under this classification since the 2011 amendment. The prohibition applies to the substance's circulation in Ukraine.
United KingdomIllegalMisuse of Drugs Act 197139
Controlled as a Class A substance under the Misuse of Drugs Act 1971 through the phenethylamine catch-all clause. In 1999, the Home Office effectively placed PiHKAL-associated compounds into Class A.
References
Source Pages
Citations
- New designer drug, 2,5-dimethoxy-4-propylthio-beta-phenethylamine (2C-T-7): studies on its metabolism and toxicological detection in rat urine using gas chromatography/mass spectrometry. pubmed.ncbi.nlm.nih.gov (n.d.). https://doi.org/10.1002/jms.78412
- Denis S Theobald, & Hans H Maurer. (January 2007). Identification of monoamine oxidase and cytochrome P450 isoenzymes involved in the deamination of phenethylamine-derived designer drugs (2C-series). Biochemical Pharmacology, 73(2), 287–297. https://doi.org/10.1016/j.bcp.2006.09.02212
- Platoni, Kara. (2002-05-01). 2C-T-7's Bad Trip. East Bay Express. https://eastbayexpress.com/2c-t-7s-bad-trip-1/123
- Therapeutic Goods (Poisons Standard—February 2026) Instrument 2026. legislation.gov.au (n.d.). https://www.legislation.gov.au/F2026L00060/latest/text/main.b35eaa308a0ad9ec.js1
- Suchtgiftverordnung. ris.bka.gv.at (n.d.). https://ris.bka.gv.at/NormDokument.wxe?Abfrage=Bundesnormen&Anlage=5&Artikel=&FassungVom=2026-01-01&Gesetzesnummer=10011053&Paragraf=&Uebergangsrecht=1
- Royal Decree of 6 September 2017 regulating narcotic drugs and psychotropic substances. ejustice.just.fgov.be (n.d.). https://www.ejustice.just.fgov.be/eli/besluit/2017/09/06/2017031231/justel1
- Royal Decree of 6 September 2017 regulating narcotic drugs and psychotropic substances. fagg-afmps.be (n.d.). https://www.fagg-afmps.be/nl/MENSELIJK_gebruik/bijzondere_producten/speciaal_gereglementeerde_stoffen/verdovende_middelen_psychotropen/wetgeving_substanties1
- Portaria SVS/MS nº 344/1998, Lista F2. gov.br (n.d.). https://www.gov.br/anvisa/pt-br/assuntos/medicamentos/controlados/arquivos/copy2_of_RESOLUORDCN607DE23DEFEVEREIRODE2022RESOLUORDCN607DE23DEFEVEREIRODE2022DOUImprensaNacional.pdf1
- Controlled Drugs and Substances Act. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/section-sched95602.html1
- Order Amending Schedule III to the Controlled Drugs and Substances Act (2C-phenethylamines) – SOR/2016-73. (2016). https://gazette.gc.ca/rp-pr/p2/2016/2016-05-04/html/sor-dors73-eng.html1
Further Reading
Article Status
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Recent changes8 human edits · latest
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31 July 2026
24 January 2026
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
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