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LSM-775

This article is a stubmissing:
Subjective Effects
Pharmacology
Tolerance
History & Culture
LSM-775 molecule structureLSM-775 molecule structure
Lysergic acid morpholide
LSM, LA-Morph, Morpholine lysergamide, N-Morpholinyllysergamide
Psychoactive Class
Chemical Class

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold250 µg
Light500-750 µg
Moderate750-1250 µg
Strong1250-1500 µg
Heavy1500+ µg

Duration

Onset25-45 minutes
After Effects1-16 hours
Total8-13 hours

Subjective Effects

Subjective Effects not written up yet

Pharmacology

Pharmacology not written up yet

Interactions

Dangerous

Highest risk

These combinations are considered extremely harmful and should always be avoided. Reactions to these drugs taken in combination are highly unpredictable and have a potential to cause death.

Unsafe

Avoid

There is considerable risk of physical harm when taking these combinations, they should be avoided where possible.

Caution

Use caution

These combinations are not usually physically harmful, but may produce undesirable effects, such as physical discomfort or overstimulation. Extreme use may cause physical health issues. Synergistic effects may be unpredictable. Care should be taken when choosing to use this combination.

Powered by TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

Extremely Low

LSM-775 is not expected to be habit-forming, and repeated administration may reduce the urge to take it again. Like many psychedelics, it likely has an inherent self-limiting pattern of use.

Toxicity

Lethal Dosage

The precise toxic dose is not known. Scientific studies have not evaluated recreational LSM-775 toxicity or its long-term health effects.

Cardiovascular

Compared with LSD, LSM-775 shows less evidence of cardiovascular stimulation and peripheral toxicity; intoxication may still involve hypotension, hypertension, or tachycardia.

Gastrointestinal

Nausea is a common adverse effect and may be intense enough to make the experience much less pleasant; vomiting can also occur.

Psychosis Risk

Low

As with other psychedelics, there is potential for adverse psychological reactions including anxiety, paranoia, and panic attacks, though anxiety may be less common than with other psychedelics. Psychosis risk may be elevated in susceptible individuals or when combined with other substances.

Seizure Risk

Low

Seizure risk is inferred from LSD-associated reports. The main concern appears to be for people with genetic susceptibility, especially when stressors such as dehydration, fatigue, or undernourishment are present.

History & Culture

History & Culture not written up yet

Legality

By Country

Illegal1
Germany flagGermanyIllegal (analog/blanket ban)
Legal / decriminalized1
United States flagUnited StatesUncontrolled
Not scheduled1
Switzerland flagSwitzerlandNot scheduled

References

Source Pages

  1. Bluelight: The Big & Dandy LSM-775 Thread
  2. Erowid Experience Vaults: LSM-775
  3. Isomer Design (TiHKAL/PiHKAL)
  4. Isomer Design: LSM-775
  5. PsychonautWiki
  6. Shulgin: TiHKAL - LSD-25 Entry
  7. The Drug Classroom
  8. TripSit Factsheets
  9. Wikipedia

Citations

  1. Verordnung der Bundesregierung: Verordnung zur Änderung der Anlage des Neue-psychoaktive-Stoffe-Gesetzes und von Anlagen des Betäubungsmittelgesetzes. bundesgesundheitsministerium.de (n.d.). https://www.bundesgesundheitsministerium.de/fileadmin/Dateien/3_Downloads/Gesetze_und_Verordnungen/GuV/N/NpSG_BtMG_VO_AEnd_Anlagen.pdf1
  2. Bundesgesetzblatt 2019 Teil I Nr. 27: Verordnung zur Änderung der Anlage des Neue-psychoaktive-Stoffe-Gesetzes und von Anlagen des Betäubungsmittelgesetzes. bundesgesundheitsministerium.de (n.d.). https://www.bundesgesundheitsministerium.de/fileadmin/Dateien/3_Downloads/Gesetze_und_Verordnungen/GuV/N/NPS_BtM_RegV_Bgbl.pdf1
  3. Neue-psychoaktive-Stoffe-Gesetz (NpSG), Anlage 1. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/npsg/anlage_1.html1
  4. Neue-psychoaktive-Stoffe-Gesetz (NpSG), § 2 Begriffsbestimmungen. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/npsg/__2.html1
  5. Neue-psychoaktive-Stoffe-Gesetz (NpSG), § 3 Unerlaubter Umgang mit neuen psychoaktiven Stoffen. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/npsg/__3.html1
  6. Neue-psychoaktive-Stoffe-Gesetz (NpSG), § 4 Strafvorschriften. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/npsg/__4.html1
  7. Neue-psychoaktive-Stoffe-Gesetz (NpSG), § 1 Anwendungsbereich. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/npsg/__1.html1
  8. Neue-psychoaktive-Stoffe-Gesetz (NpSG), current consolidated text. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/npsg/BJNR261510016.html1
  9. Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic acid morpholide (LSM-775). pmc.ncbi.nlm.nih.gov (n.d.). https://pmc.ncbi.nlm.nih.gov/articles/PMC6230476/1
  10. PubChem CID 199507 property record. pubchem.ncbi.nlm.nih.gov (n.d.). https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/199507/property/IUPACName,Title,CanonicalSMILES,MolecularFormula/JSON1

Further Reading

  1. Brandt et al. (2018): Return of the Lysergamides Part IV
  2. Brandt et al. (2018): Return of the Lysergamides Part IV (DOI)
  3. Gogerty & Dille (1957): Pharmacology of d-LSM

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed — this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

Times are UTCNewest first

24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

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