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Adinazolam

This article is a stubmissing:
Subjective Effects
Pharmacology
Tolerance
History & Culture
Legality
Adinazolam molecule structureAdinazolam molecule structure
8-Chloro-1-((dimethylamino)methyl)-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
Deracyn, U-41,123, U-41123, Adinazolamum

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold~5 mg
Light5-15 mg
Moderate15-30 mg
Strong30-50 mg
Heavy50+ mg

Duration

Onset10-25 minutes
After Effects1-16 hours
Total2-5 hours

Subjective Effects

Subjective Effects not written up yet

Reagent Testing

Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.

Marquis(MQ)
No reaction
No reaction
Mecke(ME)
No reaction
No reaction
Mandelin(MD)
No reaction
No reaction
Liebermann(LB)
No reaction
No reaction
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Pharmacology

Pharmacology not written up yet

Interactions

Dangerous

Highest risk

These combinations are considered extremely harmful and should always be avoided. Reactions to these drugs taken in combination are highly unpredictable and have a potential to cause death.

AlcoholGHB/GBLOpioidsTramadol

Unsafe

Avoid

There is considerable risk of physical harm when taking these combinations, they should be avoided where possible.

DiphenhydraminePCP

Caution

Use caution

These combinations are not usually physically harmful, but may produce undesirable effects, such as physical discomfort or overstimulation. Extreme use may cause physical health issues. Synergistic effects may be unpredictable. Care should be taken when choosing to use this combination.

DXMKetamineMXE
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Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

High

Extended use carries the possibility of psychological dependence, where individuals may become reliant on the medication to manage anxiety symptoms. As a benzodiazepine, it is classified as habit-forming.

Physical

High

Prolonged use can result in physical dependence. Reducing the dose too quickly may cause withdrawal, from rebound anxiety and insomnia through severe outcomes such as seizures.

Toxicity

Central Nervous System

Prolonged use may contribute to cognitive impairment affecting memory, concentration, and overall cognitive function; these effects are associated with extended therapeutic or recreational use patterns.

Seizure Risk

Moderate

Seizures can occur as a withdrawal symptom following rapid dose reduction or cessation after prolonged use. This risk is associated with benzodiazepine dependence rather than acute intoxication.

History & Culture

History & Culture not written up yet

Legality

Legality not written up yet

References

Source Pages

  1. DrugBank: Adinazolam
  2. TripSit: Factsheet – Adinazolam
  3. Wikipedia

Further Reading

  1. Amsterdam et al. 1986 - Adinazolam and imipramine in major depressive disorder
  2. Brogden RN et al. - Adinazolam review of pharmacology & therapeutic use
  3. Brunetti et al. 2021 - Designer Benzodiazepines: A Review of Toxicology and Public Health Risks
  4. Feighner JP et al. 1990 - Controlled trial of adinazolam vs desipramine in geriatric depression
  5. Feighner JP et al. Controlled trial of adinazolam vs desipramine in geriatric depression
  6. Moosmann et al. 2016 - Characterization and metabolism of designer benzodiazepines
  7. Pieters et al. 2021 - 'New/Designer Benzodiazepines': Analysis of Literature and Trip Reports
  8. Psychotropics Database – Adinazolam monograph
  9. Reddit user reports compilation (search query: "Adinazolam experience")
  10. Schütz E. Pharmacokinetics of adinazolam in humans
  11. Sethy et al. 1984 - Determination of biological activity of adinazolam and metabolites
  12. Tripsitter Adinazolam: A Powerful Benzodiazepine Known For Causing Mental Unpleasantness
  13. Venkatakrishnan et al. 1998 - Hepatic biotransformation of adinazolam and N-desmethyladinazolam

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed — this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

Times are UTCNewest first

24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

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