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3-FEA

3-FEA molecule structure3-FEA molecule structure
3-Fluoroethamphetamine
Psychoactive Class
Chemical Class

3-FEA is a novel synthetic entactogen and stimulant of the substituted amphetamine class.citation needed It is the 3-fluorinated analog of ethylamphetamine and belongs to a series of designer fluorinated amphetamines. Anecdotal reports characterize it as a moderately potent serotonin-dominant triple monoamine releaser, producing a combination of entactogenic and mild stimulant effects. Very little formal research exists regarding its pharmacology, toxicity, or safety profile in humans.

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold~15 mg
Light15-35 mg
Moderate35-70 mg
Strong70-90 mg
Heavy90+ mg

Duration

Onset20-50 minutes
Come Up30-60 minutes
Peak1.5-2.5 hours
Offset2-3 hours
After Effects1-12 hours
Total4-6 hours

Subjective Effects

Legacy content. A statistically backed ontology from Mindstate Design Labs is coming soon.

3-FEA produces a mixed stimulant and entactogen-leaning experience consistent with its action as a releaser of serotonin, dopamine, and norepinephrine. Its relatively strong serotonin release compared to other ethylamphetamine derivatives lends the experience a warmer, mood-elevating character than that of purely dopaminergic stimulants, though its effects are generally regarded as mild and short-lived relative to classical entactogens. Detailed phenomenological documentation of this compound remains limited.

Physical

Cognitive

The headspace is typically described as a gentle mood lift with mild euphoria and a subtle sense of emotional warmth and sociability, without significant alteration of thought structure. In high dosages it becomes much more like that of an entactogen such as MDMA due to its triple monoamine release.

Reagent Testing

Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.

Marquis(MQ)
white → yellow2 → orange1
Liebermann(LB)
white → orange2
Morr(MO)
pink2 → green1
Simons(SI)
white → blue3
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Pharmacology

Pharmacodynamics

3-FEA acts primarily as a monoamine releasing agent, elevating levels of serotonin, dopamine, and norepinephrine in the brain.citation needed It may also partially inhibit reuptake at these transporters, though this has not been formally confirmed. Relative to unsubstituted ethylamphetamine, 3-FEA shows enhanced serotonin release, though available characterizations differ regarding its relative dopamine and norepinephrine releasing potencies. In animal studies, it produced the strongest reinforcing effects among a range of 3-substituted ethamphetamine derivatives tested, despite not being the most potent dopamine releaser in that series.

Pharmacokinetics

There have been no studies on the pharmacokinetic profile of 3-FEA and the metabolism of 3-FEA is unknown.

Metabolitesnone documented yet

Interactions

Dangerous

Highest risk

These combinations are considered extremely harmful and should always be avoided. Reactions to these drugs taken in combination are highly unpredictable and have a potential to cause death.

2C-T-x compounds5-MeO-xxT tryptaminesAMTAlcoholCaffeineCannabisCocaineDOx compoundsDXMKetamineMAOIsMethoxetamineNBOMe compoundsOpioidsPCPTramadol
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Tolerance

Tolerance timelines are rules of thumb, not exact schedules, and vary widely between individuals and use patterns.

Full Tolerance
Repeated or sustained 3-FEA use can produce tolerance across many effects, leading users to need larger doses for similar results.
Baseline Reset
3-7 days
Half Tolerance
2-3 days
Cross Tolerance

Dopaminergic stimulants, Serotonergic stimulants, Entactogens (including MDMA), Amphetamines

Harm Potential

Addiction & Dependence

Psychological

Moderate

Described as likely moderately addictive with a high potential for abuse, capable of causing psychological dependence in some users. Compulsive redosing is commonly reported, particularly during or immediately following the peak effects. Cravings may develop with chronic use.

Physical

Low

Withdrawal effects may occur if use is suddenly stopped after dependence has developed, though available reports emphasize psychological rather than physical dependence mechanisms.citation needed

Toxicity

Cardiovascular

Due to its serotonin-releasing entactogenic properties, 3-FEA may display significant activity at the 5-HT2B receptor, which could make it cardiotoxic with long-term or heavy use, similar to MDMA and fenfluramine;citation needed acute cardiovascular strain during intoxication has also been reported.

Psychosis Risk

As an amphetamine derivative, abuse at high dosages for prolonged periods can potentially result in stimulant psychosis presenting with paranoia, hallucinations, or delusions. Based on reviews of amphetamine-induced psychosis, approximately 5-15% of affected users fail to recover completely, though antipsychotics effectively resolve acute symptoms.citation needed Psychosis very rarely arises from cautious, sparing use at moderate doses.

History & Culture

3-Fluoroethamphetamine belongs to a series of designer fluorinated amphetamine derivatives that emerged in the 2010s, which includes related compounds such as 2-FA, 2-FMA, 3-FA, 4-FMA, and 4-FA. These substances were developed as novel psychoactive compounds for the research chemical market.

Legality

By Country

Illegal5
Austria flagAustriaIllegal
Canada flagCanadaIllegal (analog/blanket ban)
New Zealand flagNew ZealandIllegal (analog/blanket ban)
Switzerland flagSwitzerlandIllegal (analog/blanket ban)
United Kingdom flagUnited KingdomIllegal
Controlled / restricted1
Germany flagGermanyControlled (NpSG)
Not scheduled2
United States flagUnited StatesUnscheduled (Analogue Act applies)
France flagFranceNot scheduled

References

Source Pages

  1. Bluelight: 3-FEA 26mg oral first-time experience (2017)
  2. Bluelight: 3-FEA compound thread (2018)
  3. Bluelight: 3-FEA large dose discussion (2021)
  4. Isomer Design (TiHKAL/PiHKAL)
  5. PsychonautWiki
  6. TripSit Factsheets
  7. Wikipedia

Citations

  1. RIS - Neue-Psychoaktive-Substanzen-Verordnung § 1 - Bundesrecht konsolidiert, Fassung vom 28.08.2026. ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/NormDokument.wxe?Abfrage=Bundesnormen&Anlage=&Artikel=&FassungVom=2026-08-28&Gesetzesnummer=20007642&Paragraf=1&Uebergangsrecht=1
  2. RIS - Neue-Psychoaktive-Substanzen-Verordnung Anlage II, BGBl. II Nr. 106/2024. ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/Dokumente/Bundesnormen/NOR40261441/II_106_2024_Anlage_II.pdf1
  3. RIS - Neue-Psychoaktive-Substanzen-Gesetz § 2 - Bundesrecht konsolidiert, Fassung vom 28.08.2026. ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/NormDokument.wxe?Abfrage=Bundesnormen&Anlage=&Artikel=&FassungVom=2026-08-28&Gesetzesnummer=20007605&Paragraf=2&Uebergangsrecht=1
  4. RIS - Neue-Psychoaktive-Substanzen-Gesetz § 4 - Bundesrecht konsolidiert, Fassung vom 28.08.2026. ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/NormDokument.wxe?Abfrage=Bundesnormen&Anlage=&Artikel=&FassungVom=2026-08-28&Gesetzesnummer=20007605&Paragraf=4&Uebergangsrecht=1
  5. RIS - Neue-Psychoaktive-Substanzen-Gesetz § 5 - Bundesrecht konsolidiert, Fassung vom 28.08.2026. ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/NormDokument.wxe?Abfrage=Bundesnormen&Anlage=&Artikel=&FassungVom=2026-08-28&Gesetzesnummer=20007605&Paragraf=5&Uebergangsrecht=1
  6. RIS - Suchtgiftverordnung Anhang IV - Bundesrecht konsolidiert, current RIS text. ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/NormDokument.wxe?Abfrage=Bundesnormen&Anlage=4&Artikel=&Gesetzesnummer=10011053&Paragraf=&Uebergangsrecht=1
  7. RIS - Suchtgiftverordnung Anhang IV, NOR40279095 (BGBl. II Nr. 180/2026). ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/Dokumente/Bundesnormen/NOR40279095/NOR40279095.pdf1
  8. PubChem CID 57458869 compound properties for 3-FEA. pubchem.ncbi.nlm.nih.gov (n.d.). https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/57458869/property/IUPACName,CanonicalSMILES,IsomericSMILES,MolecularFormula,InChIKey/JSON1
  9. PubChem CID 57458869 synonyms for 3-FEA. pubchem.ncbi.nlm.nih.gov (n.d.). https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/57458869/synonyms/JSON1
  10. Controlled Drugs and Substances Act, current Schedule I. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/section-sched95314.html1

Further Reading

  1. Identification and characterization of 3-fluoroethamphetamine in seized material (2018)
  2. PubChem: CID 57458869 - 3-Fluoroethamphetamine
  3. Tessel & Woods - N-ethylamphetamine self-injection in rhesus monkeys (1978)
  4. Withdrawal from 3-Fluoroethamphetamine study (2024)

Article Status

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    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

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Recent changes8 human edits · latest

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29 August 2026

  1. Lyrea · Reworded 21 words in Subjective EffectsNotes › Cognitive

  2. Lyrea · Updated the article

24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

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