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2C-N

This article is a stubmissing:
Subjective Effects
Pharmacology
Tolerance
History & Culture
2C-N molecule structure2C-N molecule structure
2,5-Dimethoxy-4-nitrophenethylamine
4-Nitro-2,5-dimethoxyphenethylamine
Psychoactive Class
Psychedelic

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold~100 mg
Light100 mg
Moderate100-125 mg
Strong125-150 mg
Heavy150+ mg

Duration

Onset15-45 minutes
After Effects2-4 hours
Total4-6 hours

Subjective Effects

Subjective Effects not written up yet

Pharmacology

Pharmacology not written up yet

Interactions

Dangerous

Highest risk

These combinations are considered extremely harmful and should always be avoided. Reactions to these drugs taken in combination are highly unpredictable and have a potential to cause death.

AMTLithium

Unsafe

Avoid

There is considerable risk of physical harm when taking these combinations, they should be avoided where possible.

Tramadol

Caution

Use caution

These combinations are not usually physically harmful, but may produce undesirable effects, such as physical discomfort or overstimulation. Extreme use may cause physical health issues. Synergistic effects may be unpredictable. Care should be taken when choosing to use this combination.

2C-T-x compounds5-MeO-xxT tryptaminesAmphetaminesCannabisCocaineDOx compoundsMAOIsMescalineNBOMe compounds
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Tolerance

Tolerance not written up yet

Harm Potential

Toxicity

Lethal Dosage

No lethal-dose or LD50 data were identified. MAOIs may potentiate 2C drugs such as 2C-N and may result in overdose and serious toxicity.

History & Culture

History & Culture not written up yet

Legality

By Country

Illegal3
United States flagUnited StatesIllegal
Canada flagCanadaIllegal
United Kingdom flagUnited KingdomIllegal

References

Source Pages

  1. Bluelight: The Big & Dandy 2C-N Thread
  2. Isomer Design (TiHKAL/PiHKAL)
  3. Isomer Design: 2C-N (PIHKAL entry)
  4. PiHKAL #34: 2C-N
  5. TripSit Factsheet: 2C-N
  6. Wikipedia
  7. Wikipedia: 2C N
  8. Wikipedia: 2C psychedelics

Citations

  1. Controlled Drugs and Substances Act — current consolidated Schedule III. laws-lois.justice.gc.ca (n.d.). https://www.laws-lois.justice.gc.ca/eng/acts/C-38.8/section-sched95602.html1
  2. Controlled Drugs and Substances Act, section 4 — Possession of substance. laws-lois.justice.gc.ca (n.d.). https://www.laws-lois.justice.gc.ca/eng/acts/C-38.8/section-4.html1
  3. Controlled Drugs and Substances Act, section 5 — Trafficking in substance. laws-lois.justice.gc.ca (n.d.). https://www.laws-lois.justice.gc.ca/eng/acts/C-38.8/section-5.html1
  4. Controlled Drugs and Substances Act, section 6 — Importing and exporting. laws-lois.justice.gc.ca (n.d.). https://www.laws-lois.justice.gc.ca/eng/acts/C-38.8/section-6.html1
  5. Controlled Drugs and Substances Act, section 7 — Production of substance. laws-lois.justice.gc.ca (n.d.). https://www.laws-lois.justice.gc.ca/eng/acts/C-38.8/section-7.html1
  6. Order Amending Schedule III to the Controlled Drugs and Substances Act (2C-phenethylamines), SOR/2016-73. gazette.gc.ca (n.d.). https://gazette.gc.ca/rp-pr/p2/2016/2016-05-04/html/sor-dors73-eng.html1
  7. Controlled Drugs and Substances Act — archived Schedule III effective 2016-10-31. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/c-38.8/section-sched95602-20161031.html1
  8. Food and Drug Regulations, Part J schedule — current Part I restricted drugs. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/regulations/C.R.C.%2C_c._870/page-146.html1
  9. Food and Drug Regulations, Part J — restricted-drug definitions and authorized possession. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/regulations/C.R.C.%2C_c._870/page-110.html1
  10. PubChem PUG REST compound properties for CID 10036637. pubchem.ncbi.nlm.nih.gov (n.d.). https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/10036637/property/IUPACName,Title,MolecularFormula,CanonicalSMILES/JSON1

Further Reading

  1. Identification of 5-HT2A receptor signaling pathways associated with psychedelic potential

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed — this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

Times are UTCNewest first

24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

All changes to this article · Site-wide recent changes

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