Citation noticeOur citation system is being overhauled
References and citation markers may currently be incomplete, mismatched, or incorrect. This system is being rebuilt and reviewed before the full site launch.
2-Aminoindane
2-Aminoindane is a synthetic stimulant of the aminoindane class and a rigid structural analogue of amphetamine in which the propane chain is cyclized back onto the benzene ring. It first appeared on the research chemical market around 2003 and has been sold as a designer drug. Its effects have been compared to those of benzylpiperazine and methamphetamine, though very little is known about its recreational use profile.
Dosage & Duration
Dosage
Doses are population estimates that vary widely between individuals.
Duration
Subjective Effects
Legacy content. A statistically backed ontology from Mindstate Design Labs is coming soon.
Effects vary widely by individual, dose, and context.
Physical
The physical effects of 2-AI can be broken down into several components which progressively intensify proportional to dosage.
Cognitive
The general head space of 2-AI is described by many as one of mental stimulation, increased focus, and euphoria. It contains a large number of typical stimulant cognitive effects. Although negative side effects are usually mild at low to moderate doses, they become increasingly likely to manifest themselves with higher amounts or extended usage. This particularly holds true during the offset of the experience.
Visual
Pharmacology
Pharmacodynamics
2-Aminoindane acts as a monoamine releasing agent with selectivity for the norepinephrine transporter (NET) and dopamine transporter (DAT). It partially substitutes for amphetamine in rodent drug discrimination tests.
Pharmacokinetics
Interactions
An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.
Tolerance
Tolerance timelines are rules of thumb, not exact schedules, and vary widely between individuals and use patterns.
Dopaminergic stimulants
Harm Potential
Addiction & Dependence
Psychological
Moderate2-Aminoindane is moderately addictive, carries a high potential for abuse, and can cause psychological dependence. Users report a strong urge to take more within a few hours and again the following day. Long-term use can result in cravings if use is stopped suddenly.
Physical
Physical dependence has not been specifically characterized. While withdrawal effects are mentioned in the context of chronic use, available information primarily addresses psychological rather than physical dependence.
Psychosis Risk
Abuse at high dosages for prolonged periods can result in stimulant psychosis presenting with paranoia, hallucinations, or delusions. Research on similar stimulants suggests 5-15% of users experiencing stimulant-induced psychosis may not fully recover, though antipsychotic medications are effective at resolving acute symptoms.
History & Culture
2-Aminoindane emerged on the research chemical market around 2003, becoming available primarily through online vendors as a designer drug. As an amphetamine analogue with stimulant properties, it attracted interest within the research chemical community despite very limited documentation of its…
Legality
By Country
References
Citations
- Decreto 560/2019 (Anexo II; texto actualizado). argentina.gob.ar (n.d.). https://www.argentina.gob.ar/normativa/nacional/decreto-560-2019-326675/actualizacion1
- Decreto 560/2019 (Anexo II; texto actualizado). argentina.gob.ar (n.d.). https://www.argentina.gob.ar/normativa/326675_dec560-2_pdf/archivo1
- Decreto 560/2019 (Anexo II; texto actualizado). argentina.gob.ar (n.d.). https://www.argentina.gob.ar/normativa/nacional/decreto-122-2026-423520/texto1
- New South Wales Drug Misuse and Trafficking Act 1985, Schedule 1. legislation.nsw.gov.au (n.d.). https://legislation.nsw.gov.au/view/whole/html/inforce/current/act-1985-2261
- New South Wales Drug Misuse and Trafficking Act 1985, Schedule 1. legislation.nsw.gov.au (n.d.). https://legislation.nsw.gov.au/view/whole/html/inforce/2018-06-21/act-1985-2261
- Neue-Psychoaktive-Substanzen-Verordnung (NPSV), Anlage II Ziffer 5, under the Neue-Psychoaktive-Substanzen-Gesetz (NPSG). ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/geltendefassung/bundesnormen/20007642/npsv%2C%20fassung%20vom%2028.07.2021.pdf1
- Neue-Psychoaktive-Substanzen-Verordnung (NPSV), Anlage II Ziffer 5, under the Neue-Psychoaktive-Substanzen-Gesetz (NPSG). ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/eli/bgbl/i/2011/146/P3/NOR401344461
- Neue-Psychoaktive-Substanzen-Verordnung (NPSV), Anlage II Ziffer 5, under the Neue-Psychoaktive-Substanzen-Gesetz (NPSG). ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/eli/bgbl/i/2011/146/P4/NOR401344471
- Royal Decree of 6 September 2017 regulating narcotic and psychotropic substances (Annex IVa). ejustice.just.fgov.be (n.d.). https://www.ejustice.just.fgov.be/eli/arrete/2017/09/06/2017031231/justel1
- Royal Decree of 6 September 2017 regulating narcotic and psychotropic substances (Annex IVa). afmps-fagg.be (n.d.). https://www.afmps-fagg.be/fr/humain/produits_particuliers/subst_specialement_reglementees/stupefiants_et_psychotropes/substances1
Article Status
Step 1 · Automated synthesisAn autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.
- Step 2 · First-pass reviewPending
Not yet reviewed — this article is pending editorial review by Lyrea.
- Step 3 · Citation reviewPending
No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.
Recent changes7 human edits · latest
Times are UTCNewest first
24 January 2026
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Suggest an edit
Spotted a mistake, an outdated claim, or something missing from the 2-Aminoindane article? Send the editors a private note. Feedback lands in a moderation queue and is never shown on the site.
Wish to give generalised feedback? You can do so here.