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2-Aminoindane

2-Aminoindane molecule structure2-Aminoindane molecule structure
Psychoactive Class
Chemical Class

2-Aminoindane is a synthetic stimulant of the aminoindane class and a rigid structural analogue of amphetamine in which the propane chain is cyclized back onto the benzene ring. It first appeared on the research chemical market around 2003 and has been sold as a designer drug. Its effects have been compared to those of benzylpiperazine and methamphetamine, though very little is known about its recreational use profile.

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold~3 mg
Light5-10 mg
Moderate10-20 mg
Strong20-40 mg
Heavy40+ mg

Duration

Onset10-30 minutes
After Effects2-4 hours
Total1-2 hours

Subjective Effects

Legacy content. A statistically backed ontology from Mindstate Design Labs is coming soon.

Effects vary widely by individual, dose, and context.

Physical

The physical effects of 2-AI can be broken down into several components which progressively intensify proportional to dosage.

Cognitive

The general head space of 2-AI is described by many as one of mental stimulation, increased focus, and euphoria. It contains a large number of typical stimulant cognitive effects. Although negative side effects are usually mild at low to moderate doses, they become increasingly likely to manifest themselves with higher amounts or extended usage. This particularly holds true during the offset of the experience.

Visual

Forked from Subjective Effect Documentation byJosie Kins September 2015.

Pharmacology

Pharmacodynamics

2-Aminoindane acts as a monoamine releasing agent with selectivity for the norepinephrine transporter (NET) and dopamine transporter (DAT). It partially substitutes for amphetamine in rodent drug discrimination tests.

Pharmacokinetics

Absorption & half-lifenot documented yetMetabolitesnone documented yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance timelines are rules of thumb, not exact schedules, and vary widely between individuals and use patterns.

Full Tolerance
Tolerance to many of the effects develops with prolonged and repeated use, resulting in users needing increasingly larger doses to achieve the same effects.
Baseline Reset
1-2 weeks
Half Tolerance
3-7 days
Cross Tolerance

Dopaminergic stimulants

Harm Potential

Addiction & Dependence

Psychological

Moderate

2-Aminoindane is moderately addictive, carries a high potential for abuse, and can cause psychological dependence. Users report a strong urge to take more within a few hours and again the following day. Long-term use can result in cravings if use is stopped suddenly.

Physical

Physical dependence has not been specifically characterized. While withdrawal effects are mentioned in the context of chronic use, available information primarily addresses psychological rather than physical dependence.

Psychosis Risk

Abuse at high dosages for prolonged periods can result in stimulant psychosis presenting with paranoia, hallucinations, or delusions. Research on similar stimulants suggests 5-15% of users experiencing stimulant-induced psychosis may not fully recover, though antipsychotic medications are effective at resolving acute symptoms.

History & Culture

2-Aminoindane emerged on the research chemical market around 2003, becoming available primarily through online vendors as a designer drug. As an amphetamine analogue with stimulant properties, it attracted interest within the research chemical community despite very limited documentation of its

Legality

By Country

Illegal20
Argentina flagArgentinaIllegal (analog/blanket ban)
Australia flagAustraliaIllegal
Austria flagAustriaIllegal
Belgium flagBelgiumIllegal (analog/blanket ban)
China flagChinaIllegal
Denmark flagDenmarkIllegal
Finland flagFinlandIllegal
Germany flagGermanyIllegal
Ireland flagIrelandIllegal
Israel flagIsraelIllegal
Japan flagJapanIllegal
Netherlands flagNetherlandsIllegal (analog/blanket ban)
Poland flagPolandIllegal
Portugal flagPortugalIllegal
Russia flagRussiaIllegal
Singapore flagSingaporeIllegal
South Africa flagSouth AfricaIllegal (analog/blanket ban)
Sweden flagSwedenIllegal
Turkey flagTurkeyIllegal
United Kingdom flagUnited KingdomIllegal
Controlled / restricted2
United States flagUnited StatesRestricted
Switzerland flagSwitzerlandRestricted

References

Citations

  1. Decreto 560/2019 (Anexo II; texto actualizado). argentina.gob.ar (n.d.). https://www.argentina.gob.ar/normativa/nacional/decreto-560-2019-326675/actualizacion1
  2. Decreto 560/2019 (Anexo II; texto actualizado). argentina.gob.ar (n.d.). https://www.argentina.gob.ar/normativa/326675_dec560-2_pdf/archivo1
  3. Decreto 560/2019 (Anexo II; texto actualizado). argentina.gob.ar (n.d.). https://www.argentina.gob.ar/normativa/nacional/decreto-122-2026-423520/texto1
  4. New South Wales Drug Misuse and Trafficking Act 1985, Schedule 1. legislation.nsw.gov.au (n.d.). https://legislation.nsw.gov.au/view/whole/html/inforce/current/act-1985-2261
  5. New South Wales Drug Misuse and Trafficking Act 1985, Schedule 1. legislation.nsw.gov.au (n.d.). https://legislation.nsw.gov.au/view/whole/html/inforce/2018-06-21/act-1985-2261
  6. Neue-Psychoaktive-Substanzen-Verordnung (NPSV), Anlage II Ziffer 5, under the Neue-Psychoaktive-Substanzen-Gesetz (NPSG). ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/geltendefassung/bundesnormen/20007642/npsv%2C%20fassung%20vom%2028.07.2021.pdf1
  7. Neue-Psychoaktive-Substanzen-Verordnung (NPSV), Anlage II Ziffer 5, under the Neue-Psychoaktive-Substanzen-Gesetz (NPSG). ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/eli/bgbl/i/2011/146/P3/NOR401344461
  8. Neue-Psychoaktive-Substanzen-Verordnung (NPSV), Anlage II Ziffer 5, under the Neue-Psychoaktive-Substanzen-Gesetz (NPSG). ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/eli/bgbl/i/2011/146/P4/NOR401344471
  9. Royal Decree of 6 September 2017 regulating narcotic and psychotropic substances (Annex IVa). ejustice.just.fgov.be (n.d.). https://www.ejustice.just.fgov.be/eli/arrete/2017/09/06/2017031231/justel1
  10. Royal Decree of 6 September 2017 regulating narcotic and psychotropic substances (Annex IVa). afmps-fagg.be (n.d.). https://www.afmps-fagg.be/fr/humain/produits_particuliers/subst_specialement_reglementees/stupefiants_et_psychotropes/substances1

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Recent changes7 human edits · latest

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24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

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