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Cognitive fatigue

Cognitive fatigue (also called exhaustion, tiredness, lethargy, languidness, languor, lassitude, and listlessness) is medically recognized as a state usually associated with a weakening or depletion of one's mental resources. It is most commonly induced under the influence of moderate dosages of antipsychotic compounds, such as quetiapine, haloperidol, and risperidone.

Cognitive fatigue (also called exhaustion, tiredness, lethargy, languidness, languor, lassitude, and listlessness) is medically recognized as a state usually associated with a weakening or depletion of one's mental resources.12 The intensity and duration of this effect typically depends on the substance consumed and its dosage. It can also be further exacerbated by various factors such as a lack of sleep3 or food4. These feelings of exhaustion involve a wide variety of symptoms which generally include some or all of the following effects:

Cognitive fatigue is most commonly induced under the influence of moderate dosages of antipsychotic compounds,56 such as quetiapine, haloperidol, and risperidone. However, it can also occur during the withdrawal symptoms of many depressants7, and during the offset of many stimulants8.

References

See Also

External Links

  1. Cognition (Wikipedia)
  2. Fatigue (medical) (Wikipedia)

Citations

  1. American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.), 821. Arlington, VA: American Psychiatric Publishing.
  2. Mizuno, K., Tanaka, M., Yamaguti, K., Kajimoto, O., Kuratsune, H., & Watanabe, Y. (2011). Mental fatigue caused by prolonged cognitive load associated with sympathetic hyperactivity. Behavioral and brain functions, 7(1), 17.
  3. Alhola, P., & Polo-Kantola, P. (2007). Sleep deprivation: Impact on cognitive performance. Neuropsychiatric disease and treatment.
  4. Kim, J. Y., & Kang, S. W. (2017). Relationships between dietary Intake and cognitive function in healthy korean children and adolescents. Journal of lifestyle medicine, 7(1), 10.
  5. Seo, R. J., MacPherson, H., & Young, A. H. (2010). Atypical antipsychotics and other therapeutic options for treatment of resistant major depressive disorder. Pharmaceuticals, 3(12), 3522-3542.
  6. Wittkampf, L. C., Arends, J., Timmerman, L., & Lancel, M. (2012). A review of modafinil and armodafinil as add-on therapy in antipsychotic-treated patients with schizophrenia. Therapeutic advances in psychopharmacology, 2(3), 115-125.
  7. Risher-Flowers, D., Adinoff, B., Ravitz, B., Bone, G. H., Martin, P. R., Nutt, D., & Linnoila, M. (1988). Circadian rhythms of cortisol during alcohol withdrawal. Advances in alcohol & substance abuse, 7(3-4), 37-41.
  8. Lago, J. A., & Kosten, T. R. (1994). Stimulant withdrawal. Addiction, 89(11), 1477-1481.
Contributors:Josie·Kaylee·Graham