Skip to main content
L

Not yet reviewed: this article is pending editorial review by Lyrea.

Citation noticeOur citation system is being overhauled

References and citation markers may currently be incomplete, mismatched, or incorrect. This system is being rebuilt and reviewed before the full site launch.

5-MeO-DALT

5-MeO-DALT molecule structure5-MeO-DALT molecule structure
N,N-Diallyl-5-methoxytryptamine
Foxtrot
Psychoactive Class
Chemical Class
Tryptamine

5-MeO-DALT is a psychoactive tryptamine1 with short-lived effects that are reported to be primarily physical, often lacking the visual distortions typical of many psychedelics. User reports describe rapid, strong entheogenic effects and euphoric, sensual, energised feelings.1 Self-reported acute physical effects, unsubstantiated by medical observation, may include increased blood pressure and rapid heartbeat.1 The paper states that no information is available on its long-term effects1. Alexander Shulgin first synthesized and described it in 2004.

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold4-5 mg
Light5-12 mg
Moderate12-20 mg
Strong20+ mg
Heavy35+ mg

Duration

Onset10-15 minutes
Come Up15-20 minutes
Peak60-90 minutes
Offset1-2 hours

Subjective Effects

Legacy content. A statistically backed ontology from Mindstate Design Labs is coming soon.

Effects vary widely by individual, dose, and context.

Physical

The physical effects of 5-MeO-DALT can be broken down into several components which progressively intensify proportional to dosage.

Cognitive

The head space of 5-MeO-DALT is described by many as one which is both insightful and relatively normal in its thought processes even at moderate to high doses.

Visual

Geometry

The visual geometry that is present throughout the experience can be described as more similar in appearance to that of AMT than that of LSD, 2C-B or 2C-I. It can be comprehensively described as unstructured in its organization, synthetic in geometric style, intricate in complexity, small in size, slow and smooth in motion, colourful in scheme, glossy in colour, equally blurred and sharp in its edges and equally rounded and angular in its corners. They give off a synthetic feel to them that is less impressive than most of the "classical" psychedelics at any level. It has yet to be confirmed whether this compound results in either level 8A or level 8B at heavy doses.

Distortions

5-MeO-DALT presents a full and complete array of possible visual distortions.

Enhancements

5-MeO-DALT presents a full and complete array of possible visual enhancements.

Auditory

The auditory effects of 5-MeO-DALT are common in their occurrence and exhibit a full range of effects.

Forked from Subjective Effect Documentation byJosie Kins September 2015.

See also: Psychedelic Intensity Scale, Effects of psychedelics (visual, cognitive, miscellaneous)

Reagent Testing

Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.

Marquis(MQ)
white → yellow2 → brown2
Mecke(ME)
white → yellow2 → brown2 → red3
Mandelin(MD)
yellow2 → red2 → black3
Liebermann(LB)
white → orange3 → brown3 → black3
Powered by PROtestkit.eu

Pharmacology

Pharmacodynamics

5-MeO-DALT acts primarily as a potent full agonist at serotonin 5-HT1A and 5-HT2A receptors, with 5-HT2A activity implicated in its psychedelic effects. It also agonizes 5-HT2B and 5-HT2C receptors and inhibits dopamine and serotonin reuptake through DAT and SERT. Binding affinities have also been reported at other serotonin receptors, adrenergic α2A, α2B and α2C receptors, histamine H1 and H3 receptors, κ-opioid receptors, and σ1 and σ2 receptors2, but their functional contributions remain under investigation.

Pharmacokinetics

Absorption & half-lifenot documented yetMetabolitesnone documented yet

Interactions

Dangerous

Highest risk

These combinations are considered extremely harmful and should always be avoided. Reactions to these drugs taken in combination are highly unpredictable and have a potential to cause death.

AMTMAOIsPCP

Unsafe

Avoid

There is considerable risk of physical harm when taking these combinations, they should be avoided where possible.

AmphetaminesCocaineDXMTramadol

Caution

Use caution

These combinations are not usually physically harmful, but may produce undesirable effects, such as physical discomfort or overstimulation. Extreme use may cause physical health issues. Synergistic effects may be unpredictable. Care should be taken when choosing to use this combination.

2C-T-x compounds2C-x compoundsCannabisDOx compoundsMDMAMescalineNBOMe compoundsPregabalin
Powered by TripSit

Tolerance

Tolerance timelines are rules of thumb, not exact schedules, and vary widely between individuals and use patterns.

Full Tolerance
Tolerance to 5-MeO-DALT develops almost immediately after ingestion.
Baseline Reset
In the absence of further consumption, tolerance returns to baseline after about 7 days.
Half Tolerance
After ingestion, tolerance is reduced by half in about 3 days.
Cross Tolerance

Psychedelics

Harm Potential

Toxicity

Lethal Dosage

The exact toxic dose is unknown. One reported death involved injuries sustained after a person was hit by a truck while under the influence of 5-MeO-DALT3, and a published case report describes brief loss of consciousness and visual hallucinations after consuming 5-MeO-DALT.

Cardiovascular

Self-reported acute physical effects of 5-MeO-DALT, unsubstantiated by medical observation, may include an increase in heart rate and blood pressure3, with greater cardiovascular discomfort than other psychedelics; possible toxicity has been raised for long-term or heavy use.

Skeletal muscle

Rhabdomyolysis has been reported in described cases of 5-MeO-DALT poisoning.2

Psychosis Risk

A case report described brief loss of consciousness and visual hallucinations after consumption of three 5-MeO-DALT tablets.

History & Culture

Shulgin and Shulgin first described the illicit manufacture of 5-MeO-DALT in 20044, sending material on its synthesis and effects to a research associate in May 2004. The synthesis instructions were available online5, and the compound became available…

Legality

IllegalControlled / restrictedNot scheduledNothing on file

International

5-MeO-DALT does not appear in the schedules of the 1961 Single Convention or the 1971 Convention on Psychotropic Substances, or in the precursor tables of the 1988 Convention. It is therefore not internationally scheduled under those conventions.

By Country

Illegal16
United States flagUnited StatesIllegal (analog/blanket ban)
Austria flagAustriaIllegal (analog/blanket ban)
Belgium flagBelgiumIllegal (analog/blanket ban)
Brazil flagBrazilIllegal
China flagChinaIllegal
Finland flagFinlandIllegal
Germany flagGermanyIllegal (analog/blanket ban)
Italy flagItalyIllegal (analog/blanket ban)
Japan flagJapanIllegal
Russia flagRussiaIllegal
Singapore flagSingaporeIllegal
Slovakia flagSlovakiaIllegal
Sweden flagSwedenIllegal
Switzerland flagSwitzerlandIllegal
Ukraine flagUkraineIllegal
United Kingdom flagUnited KingdomIllegal (analog/blanket ban)
Controlled / restricted1
Denmark flagDenmarkRestricted
Not scheduled1
Canada flagCanadaNot scheduled

References

Source Pages

  1. Drug Users Bible by Dominic Milton Trott
  2. Drug Users Bible: 5-MeO-DALT
  3. Erowid
  4. Erowid: 5-MeO-DALT Vault
  5. Erowid: 5-MeO-DALT Vault
  6. Isomer Design (TiHKAL/PiHKAL)
  7. Isomer Design: 5-MeO-DALT
  8. PsychonautWiki
  9. TripSit Factsheet: 5-MeO-DALT
  10. TripSit Factsheets
  11. Wikipedia

Citations

  1. The recreational tryptamine 5-MeO-DALT (N,N-diallyl-5-methoxytryptamine): A brief review. University of Hertfordshire Research Archive (2012). https://doi.org/10.1016/j.pnpbp.2012.05.0221234
  2. 43rd ECDD (2020): 5-MeO-DALT. World Health Organization (2020). https://cdn.who.int/media/docs/default-source/controlled-substances/43rd-ecdd/5-meo-dalt-final-a.pdf?sfvrsn=599b35c_412345678910111213141516
  3. The recreational tryptamine 5-MeO-DALT (N,N-diallyl-5-methoxytryptamine): a brief review. PubMed (2012). https://doi.org/10.1016/j.pnpbp.2012.05.02212
  4. WHO Expert Committee on Drug Dependence Forty-third report: Critical review report 5-Methoxy-N,N-diallyltryptamine (5-MeO-DALT). World Health Organization (2021). https://www.rsu.lv/sites/default/files/book_download/9789240023024-eng.pdf123
  5. The recreational tryptamine 5-MeO-DALT (/N,/N-diallyl-5-methoxytryptamine): A brief review. Progress in Neuro-Psychopharmacology & Biological Psychiatry (2012). https://doi.org/10.1016/j.pnpbp.2012.05.0221
  6. 5-MeO-DALT: the freebase of N,N-diallyl-5-methoxytryptamine. IUCrData (2020). https://doi.org/10.1107/s24143146200049881
  7. 我国管制毒品目录(2026年7月更新,540种+三大类). ga.sz.gov.cn (n.d.). https://ga.sz.gov.cn/SZJDZX/SZBMFW/content/post_12898420.html1
  8. 三部门联合发布最新版《非药用类麻醉药品和精神药品目录》. btgaj.xjbt.gov.cn (n.d.). https://btgaj.xjbt.gov.cn/c/2025-07-28/8428464.shtml1
  9. 非药用类麻醉药品和精神药品列管办法. gaj.panjin.gov.cn (n.d.). https://gaj.panjin.gov.cn/2015_10/08_00/content-235605.html1
  10. Decreto del Presidente della Repubblica 9 ottobre 1990, n. 309, art. 14 and art. 73. normattiva.it (n.d.). https://www.normattiva.it/uri-res/N2Ls?urn:nir:stato:decreto.del.presidente.della.repubblica:1990-10-09;309~art14!vig=1

Further Reading

  1. Brandt et al. (2017) - Analytical characterization of DALT derivatives
  2. Corkery et al. (2012) - The recreational tryptamine 5-MeO-DALT: A brief review
  3. Cozzi & Daley (2016) - Receptor binding profiles of 5-substituted-N,N-diallyltryptamines
  4. WHO Critical Review Report: 5-MEO-DALT (43rd ECDD)
  5. Jovel et al. 2013 - Delirium Due to Intoxication from the Novel Synthetic Tryptamine 5‐MeO‐DALT
  6. Dinger et al. 2016 - Cytochrome P450 inhibition potential of new psychoactive substances of the tryptamine class
  7. Klein et al. 2018 - Receptor binding profiles and behavioral pharmacology of ring-substituted N,N-diallyltryptamine analogs

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed: this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Suggest an edit

Spotted a mistake, an outdated claim, or something missing from the 5-MeO-DALT article? Send the editors a private note. Feedback lands in a moderation queue and is never shown on the site.

Wish to give generalised feedback? You can do so here.