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5-MeO-DALT
5-MeO-DALT is a lesser-known psychedelic of the tryptamine and 5-methoxytryptamine families. First synthesized and described by Alexander Shulgin, it was disclosed in 2004 and later encountered as a novel designer and recreational drug. This short-acting compound is structurally related to DALT and 5-MeO-DiPT but reportedly produces distinct effects. It typically occurs as an off-white powder and is taken orally or nasally. Reported dose-response patterns vary unusually widely, potentially reflecting misrepresented substances.
Dosage & Duration
Dosage
Doses are population estimates that vary widely between individuals.
Duration
Subjective Effects
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Effects vary widely by individual, dose, and context.
Physical
The physical effects of 5-MeO-DALT can be broken down into several components which progressively intensify proportional to dosage.
Cognitive
The head space of 5-MeO-DALT is described by many as one which is both insightful and relatively normal in its thought processes even at moderate to high doses.
Visual
Distortions
5-MeO-DALT presents a full and complete array of possible visual distortions.
Enhancements
5-MeO-DALT presents a full and complete array of possible visual enhancements.
Geometry
The visual geometry that is present throughout the experience can be described as more similar in appearance to that of AMT than that of LSD, 2C-B or 2C-I. It can be comprehensively described as unstructured in its organization, synthetic in geometric style, intricate in complexity, small in size, slow and smooth in motion, colourful in scheme, glossy in colour, equally blurred and sharp in its edges and equally rounded and angular in its corners. They give off a synthetic feel to them that is less impressive than most of the "classical" psychedelics at any level. It has yet to be confirmed whether this compound results in either level 8A or level 8B at heavy doses.
Auditory
The auditory effects of 5-MeO-DALT are common in their occurrence and exhibit a full range of effects.
See also: Psychedelic Intensity Scale, Effects of psychedelics (visual, cognitive, miscellaneous)
Pharmacology
Pharmacodynamics
5-MeO-DALT acts as a potent full agonist at the serotonin 5-HT1A and 5-HT2A receptors, with 5-HT2A activation implicated in its psychedelic-like activity. It also acts as an agonist at 5-HT2B and 5-HT2C receptors and inhibits dopamine and serotonin reuptake through DAT and SERT. Binding has additionally been reported at several other serotonin, adrenergic, histamine, opioid, and sigma receptors, suggesting that multiple targets may contribute to its overall pharmacological profile.
Pharmacokinetics
Dangerous
Highest riskThese combinations are considered extremely harmful and should always be avoided. Reactions to these drugs taken in combination are highly unpredictable and have a potential to cause death.
Unsafe
AvoidThere is considerable risk of physical harm when taking these combinations, they should be avoided where possible.
Caution
Use cautionThese combinations are not usually physically harmful, but may produce undesirable effects, such as physical discomfort or overstimulation. Extreme use may cause physical health issues. Synergistic effects may be unpredictable. Care should be taken when choosing to use this combination.
Tolerance
Tolerance timelines are rules of thumb, not exact schedules, and vary widely between individuals and use patterns.
Psychedelics
Harm Potential
Toxicity
The exact toxic dose is unknown. A death associated with behavioral intoxication has been reported.
Acute intoxication can increase heart rate and blood pressure, with cardiovascular effects reported as more uncomfortable than those of other psychedelics; possible toxicity with long-term or heavy use remains uncertain.
Rhabdomyolysis has been reported in overdose cases.
Overdose cases have involved loss of consciousness, visual hallucinations, and acute delirium.
History & Culture
Alexander Shulgin first synthesized and described 5-MeO-DALT, disclosing the compound in 2004. In May of that year, he sent information about its synthesis and effects to a research associate named Murple, after which the material circulated online. Shulgin stated that the compound had not…
Trip Reports
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Legality
International
5-MeO-DALT does not appear in the schedules of the 1961 Single Convention or the 1971 Convention on Psychotropic Substances, or in the precursor tables of the 1988 Convention. It is therefore not internationally scheduled under those conventions.
By Country
References
Source Pages
Citations
- Neue-Psychoaktive-Substanzen-Verordnung (NPSV) and Neue-Psychoaktive-Substanzen-Gesetz (NPSG). ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/GeltendeFassung.wxe?Abfrage=Bundesnormen&Gesetzesnummer=200076421
- Neue-Psychoaktive-Substanzen-Verordnung (NPSV) and Neue-Psychoaktive-Substanzen-Gesetz (NPSG). ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/Dokumente/Bundesnormen/NOR40261441/II_106_2024_Anlage_II.pdf1
- Neue-Psychoaktive-Substanzen-Verordnung (NPSV) and Neue-Psychoaktive-Substanzen-Gesetz (NPSG). ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/GeltendeFassung.wxe?Abfrage=Bundesnormen&Gesetzesnummer=200076051
- Royal Decree of 6 September 2017 regulating narcotic and psychotropic substances. etaamb.openjustice.be (n.d.). https://etaamb.openjustice.be/fr/arrete-royal-du-06-septembre-2017_n2017031231.html1
- Royal Decree of 6 September 2017 regulating narcotic and psychotropic substances. afmps.be (n.d.). https://www.afmps.be/fr/humain/produits_particuliers/subst_specialement_reglementees/stupefiants_et_psychotropes/substances1
- Portaria SVS/MS No. 344 of 12 May 1998, Annex I, Lista F2, as republished in ANVISA RDC No. 1,036 of 9 July 2026 (published 13 July 2026). anvisalegis.datalegis.net (n.d.). https://anvisalegis.datalegis.net/action/ActionDatalegis.php?acao=abrirTextoAto&tipo=RDC&numeroAto=00001036&seqAto=000&valorAno=2026&orgao=RDC/DC/ANVISA/MS&codTipo=&desItem=&desItemFim=&cod_menu=1696&cod_modulo=134&pesquisa=true1
- Portaria SVS/MS No. 344 of 12 May 1998, Annex I, Lista F2, as republished in ANVISA RDC No. 1,036 of 9 July 2026 (published 13 July 2026). gov.br (n.d.). https://www.gov.br/anvisa/pt-br/assuntos/medicamentos/controlados/lista-substancias1
- Portaria SVS/MS No. 344 of 12 May 1998, Annex I, Lista F2, as republished in ANVISA RDC No. 1,036 of 9 July 2026 (published 13 July 2026). anvisalegis.datalegis.net (n.d.). https://anvisalegis.datalegis.net/action/ActionDatalegis.php?acao=abrirTextoAto&tipo=POR&numeroAto=00000344&seqAto=000&valorAno=1998&orgao=SVS/MS&codTipo=&desItem=&desItemFim=&cod_menu=1696&cod_modulo=134&pesquisa=true1
- Controlled Drugs and Substances Act, S.C. 1996, c. 19. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/FullText.html1
- Controlled Drugs and Substances Act, S.C. 1996, c. 19. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/fra/lois/C-38.8/TexteComplet.html1
Further Reading
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Recent changes7 human edits · latest
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24 January 2026
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
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