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WARNINGREDOSING CAN TRIGGER PSYCHOSIS

PCP-like dissociatives can cause mania, paranoia, or psychosis that outlasts the high. High doses, redosing, and sleep loss raise the risk.

PCE

PCE molecule structurePCE molecule structure
N-Ethyl-1-phenylcyclohexanamine
Eticyclidine, CI-400, Cyclohexamine
Psychoactive Class
DissociativeHallucinogen
Chemical Class
Arylcyclohexylamine

PCE (eticyclidine) is a dissociative anesthetic of the arylcyclohexylamine class that produces hallucinogenic effects.citation needed It is reported to be slightly more potent than its structural relative PCP (phencyclidine). Like other arylcyclohexylamines, it carries habit-forming potential. Limited documentation exists regarding its safety profile, and users should exercise considerable caution given the scarcity of available research on its effects and risks.

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold~1 mg
Light1-3 mg
Moderate3-7 mg
Strong7-15 mg
Heavy15+ mg

Duration

After Effects1-4 hours
Total2-5 hours

Subjective Effects

Legacy content. A statistically backed ontology from Mindstate Design Labs is coming soon.

Reported as a dissociative anesthetic with hallucinogenic effects, described as slightly more potent than PCP. Available material does not detail the character or time course of the experience.

Cognitive

Dissociation

See also: Dissociative Intensity Scale, Subjective Effects of Dissociatives

Pharmacology

Pharmacodynamics

PCE (eticyclidine) is a dissociative anesthetic of the arylcyclohexylamine class.citation needed It is structurally related to phencyclidine (PCP) and is reported to be slightly more potent. Detailed receptor binding data for PCE remains limited in the available literature.

Pharmacokinetics

Absorption & half-lifenot documented yetMetabolitesnone documented yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance timelines are rules of thumb, not exact schedules, and vary widely between individuals and use patterns.

Cross Tolerance

Dissociatives, NMDA receptor antagonists

Harm Potential

Addiction & Dependence

Psychological

Classified as habit-forming, suggesting some potential for psychological dependence.citation needed

History & Culture

History & Culture not written up yet

Legality

International

PCE (eticyclidine) is internationally controlled in Schedule I of the 1971 Convention on Psychotropic Substances.

By Country

Illegal21
United States flagUnited StatesIllegal
Belgium flagBelgiumIllegal
Canada flagCanadaIllegal
Denmark flagDenmarkIllegal
Finland flagFinlandIllegal
Germany flagGermanyIllegal
India flagIndiaIllegal
Ireland flagIrelandIllegal
Italy flagItalyIllegal
Japan flagJapanIllegal
Netherlands flagNetherlandsIllegal
New Zealand flagNew ZealandIllegal
Norway flagNorwayIllegal
Philippines flagPhilippinesIllegal
Portugal flagPortugalIllegal
Russia flagRussiaIllegal
Singapore flagSingaporeIllegal
South Africa flagSouth AfricaIllegal
Spain flagSpainIllegal
Thailand flagThailandIllegal
United Kingdom flagUnited KingdomIllegal
Controlled / restricted1
Colombia flagColombiaRestricted

References

Source Pages

  1. Bluelight: PCE Bioassay Thread
  2. Bluelight: PCE Small & Handy Thread
  3. Erowid: PCE Experience Reports
  4. PsychonautWiki: PCE
  5. Wikipedia

Citations

  1. Royal Decree of 6 September 2017 regulating narcotic, psychotropic and soporific substances. ejustice.just.fgov.be (n.d.). http://www.ejustice.just.fgov.be/eli/arrete/2017/09/06/2017031231/justel1
  2. Annex II: non-official consolidated version. afmps.be (n.d.). https://www.afmps.be/sites/default/files/content/INSP/NARC/annex%20II_non%20official%20consolidated%20version.pdf1
  3. Controlled Drugs and Substances Act. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/c-38.8/page-11.html1
  4. Controlled Drugs and Substances Act. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/c-38.8/fulltext.html/10001
  5. Ministerio de Salud y Protección Social, Resolución 000116 de 2026, art. 2, Anexo Técnico No. 1. minsalud.gov.co (n.d.). https://www.minsalud.gov.co/Normatividad_Nuevo/Resolucion%20No%20116%20de%202026.pdf1
  6. Bekendtgørelse om euforiserende stoffer, BEK nr. 405 af 26. marts 2026, effective 29 March 2026. retsinformation.dk (n.d.). https://www.retsinformation.dk/eli/lta/2026/405/dan/pdf1
  7. Valtioneuvoston asetus huumausaineina pidettävistä aineista, valmisteista ja kasveista annetun valtioneuvoston asetuksen muuttamisesta (1119/2025), amending 543/2008. finlex.fi (n.d.). https://www.finlex.fi/api/media/statute/896227/mainPdf/main.pdf?timestamp=2025-12-10T08%3A09%3A32.765Z1
  8. Anlage I BtMG – Einzelnorm. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/btmg_1981/anlage_i.html1
  9. § 1 BtMG – Einzelnorm. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/btmg_1981/__1.html1
  10. The Narcotic Drugs and Psychotropic Substances Act, 1985. upload.indiacode.nic.in (n.d.). https://upload.indiacode.nic.in/showfile?actid=AC_CEN_2_2_00029_198561_1517807326222&filename=a1985-61.pdf&type=actfile1

Further Reading

  1. Kalir et al. 1969: 1-Phenylcycloalkylamine derivatives
  2. Morris & Wallach 2014: From PCP to MXE
  3. Tasman et al. 2015: Psychiatry

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed — this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

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24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

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