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WARNINGOVERDOSE, COMBINATIONS, & WITHDRAWAL CAN BE FATAL

High doses alone or ordinary doses in combination with other depressants can fatally stop breathing. After prolonged dependency, stopping suddenly can cause seizures, delirium, or death.

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Methylmethaqualone

Psychoactive Class

Depressant Sedative Anxiolytic Muscle Relaxant GABAergic

Chemical Class

Quinazolinone

Methylmethaqualone is a depressant research chemical and a more potent structural analogue of methaqualone. It is characterized by a comparatively short duration of action relative to its parent compound. The substance carries significant safety concerns, as it is suspected to be neurotoxic and has been reported to produce proconvulsive effects. Due to its limited research history and potential for harm, it should be approached with considerable caution.

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold~2 mg

Light2-5 mg

Moderate5-10 mg

Strong10-20 mg

Heavy20+ mg

Duration

After Effects1-2 hours

Total1-2 hours

Subjective Effects

Legacy content. A statistically backed ontology from Mindstate Design Labs is coming soon.

The experience is that of a classic sedative-hypnotic in the methaqualone family, dominated by anxiety relief, heavy sedation, and pronounced muscle relaxation rather than any significant sensory alteration. As the dose increases, coordination deteriorates noticeably and memory of the period after ingestion can become patchy or absent, with the sedation ultimately deepening into a hypnotic, sleep-inducing state.

Physical

The body feels heavy, relaxed, and sedated, with substantial muscle relaxation. Motor coordination is impaired, producing unsteady, clumsy movement, and the overall effect trends strongly toward sleep.

Sedation

Cognitive

The headspace is calm and anxiolytic, with a reduction in worry and mental tension. At moderate to high doses, recall of events becomes unreliable due to amnesia.

Suppressions

Pharmacology

Pharmacodynamics

Methylmethaqualone produces its sedative and hypnotic effects through agonist activity at the β subunit of the GABA-A receptor. In animal models, it has been found to be approximately three times more potent than its parent compound methaqualone.

Pharmacokinetics

Absorption & half-lifenot documented yetMetabolitesnone documented yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check

TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

Classified as habit-forming, suggesting some potential for psychological dependence.

Toxicity

Central Nervous System

The drug is suspected to be neurotoxic, though the specific conditions, mechanisms, and extent of potential neurotoxic effects have not been fully characterized.

Seizure Risk

Animal studies demonstrate that convulsions occur at doses only slightly above the effective sedative dose, indicating a very narrow safety margin. Human users have reported pro-convulsive effects, and a high number of seizures have been associated with this substance, making it particularly hazardous at elevated doses.

History & Culture

Methylmethaqualone is a designer drug analogue of methaqualone that appears to have emerged on the German black market during the late 1990s. The compound was made illegal in Germany in 1999, and around the same time, the United States Drug Enforcement Administration listed it as a "drug of forensic interest." Beyond these regulatory actions, very little documented information about this substance's history or cultural context is available.

Legality

By Country

Illegal2

United StatesIllegal (analog/blanket ban)

GermanyIllegal

References

Citations

Article Status

Step 1 · Automated synthesis
An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.
Step 2 · First-pass reviewPending
Not yet reviewed — this article is pending editorial review by Lyrea.
Step 3 · Citation reviewPending
No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest 24 Jan

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24 January 2026

23:32
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
23:25
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
23:20
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
23:15
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
22:57
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
22:42
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
22:21
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

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