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Dosage & Duration
Dosage
Doses are population estimates that vary widely between individuals.
Duration
Subjective Effects
Reagent Testing
Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.
Pharmacology
Dangerous
Highest riskThese combinations are considered extremely harmful and should always be avoided. Reactions to these drugs taken in combination are highly unpredictable and have a potential to cause death.
Tolerance
Harm Potential
Addiction & Dependence
Psychological
ModerateWith ongoing use, MDEA may produce moderate addiction risk, substantial abuse potential, and psychological dependence in some users. After dependence has formed, abrupt cessation can be followed by cravings and withdrawal effects.
Physical
LowPhysical dependence is not prominently characterized, though withdrawal effects including cravings may occur with chronic use.
Toxicity
Repeated or high doses of MDEA are likely to carry neurotoxic risk. As a potent serotonin releaser, it is believed to reduce serotonin reuptake transporter availability in the brain, and the timeline for recovery remains uncertain.
Heavy MDEA use over extended periods is likely to harm the cardiovascular system and may contribute to valvulopathy; overdose-level exposure can produce acute tachycardia and hypotension.
MDEA and related compounds are hepatotoxic; regular use may cause liver damage.
Hyperthermia is a significant acute risk, particularly with continuous activity without sufficient rest or rehydration; body temperature may rise to dangerous levels.
Overdose may cause muscle rigidity and rhabdomyolysis.
Psychosis Risk
Regular use may lead to schizophrenia-like symptoms according to available sources.
Seizure Risk
Convulsions are listed among overdose symptoms. Risk may be increased when combined with substances that lower seizure threshold.
History & Culture
Legality
International
MDEA (N-ethyl MDA) is listed in Schedule I of the 1971 Convention on Psychotropic Substances. It is not named in the schedules of the 1961 Single Convention, and it is not one of the precursor chemicals in Tables I or II of the 1988 Convention; those latter instruments therefore do not independently schedule/control exact MDEA.
By Country
References
Source Pages
Citations
- Decree 122/2026; Decree 560/2019; Law 23,737. argentina.gob.ar (n.d.). https://www.argentina.gob.ar/normativa/nacional/decreto-122-2026-423520/texto1
- Decree 122/2026; Decree 560/2019; Law 23,737. mpf.gob.ar (n.d.). https://www.mpf.gob.ar/procunar/files/2019/09/Anexo-decreto-122-2026.pdf1
- Decree 122/2026; Decree 560/2019; Law 23,737. argentina.gob.ar (n.d.). https://www.argentina.gob.ar/normativa/nacional/decreto-560-2019-326675/actualizacion1
- Decree 122/2026; Decree 560/2019; Law 23,737. argentina.gob.ar (n.d.). https://www.argentina.gob.ar/normativa/nacional/39624/actualizacion1
- Customs (Prohibited Imports) Regulations 1956. legislation.gov.au (n.d.). https://www.legislation.gov.au/F1996B03651/latest/text1
- Customs (Prohibited Imports) Regulations 1956. legislation.gov.au (n.d.). https://www.legislation.gov.au/F1996B03651/2026-07-13/2026-07-13/text/original/epub/OEBPS/document_1/document_1.html1
- Suchtmittelgesetz (SMG) §2(2), §5, §6, §8 and §27, implemented by Suchtgiftverordnung (SV), Gesetzesnummer 10011053, Annex V.1; Psychotropenverordnung (PV), Gesetzesnummer 10011054, is not the operative schedule because SMG §3/PV cover Convention Annexes III and IV, while N-Ethyl MDA is in Convention Annex I.. ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/GeltendeFassung.wxe?Abfrage=Bundesnormen&Gesetzesnummer=100110531
- Suchtmittelgesetz (SMG) §2(2), §5, §6, §8 and §27, implemented by Suchtgiftverordnung (SV), Gesetzesnummer 10011053, Annex V.1; Psychotropenverordnung (PV), Gesetzesnummer 10011054, is not the operative schedule because SMG §3/PV cover Convention Annexes III and IV, while N-Ethyl MDA is in Convention Annex I.. ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/NormDokument.wxe?Abfrage=Bundesnormen&Gesetzesnummer=10011053&Anlage=51
- Suchtmittelgesetz (SMG) §2(2), §5, §6, §8 and §27, implemented by Suchtgiftverordnung (SV), Gesetzesnummer 10011053, Annex V.1; Psychotropenverordnung (PV), Gesetzesnummer 10011054, is not the operative schedule because SMG §3/PV cover Convention Annexes III and IV, while N-Ethyl MDA is in Convention Annex I.. ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/NormDokument.wxe?Abfrage=Bundesnormen&Gesetzesnummer=10011040&Paragraf=81
- Suchtmittelgesetz (SMG) §2(2), §5, §6, §8 and §27, implemented by Suchtgiftverordnung (SV), Gesetzesnummer 10011053, Annex V.1; Psychotropenverordnung (PV), Gesetzesnummer 10011054, is not the operative schedule because SMG §3/PV cover Convention Annexes III and IV, while N-Ethyl MDA is in Convention Annex I.. ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/NormDokument.wxe?Abfrage=Bundesnormen&Gesetzesnummer=10011040&Paragraf=271
Further Reading
Article Status
Step 1 · Automated synthesisAn autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.
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Recent changes7 human edits · latest
Times are UTCNewest first
24 January 2026
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
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