A muscle cramp can be described as an involuntary temporary contraction or over shortening of muscles which may cause severe aches and pains. The onset of these muscle cramps is usually sudden while the cramp typically resolves itself spontaneously within a few seconds or minutes. Muscle cramps are often accompanied by other coinciding effects such as muscle twitching and stimulation. They are most commonly induced under the influence of heavy dosages of stimulating psychedelics compounds, such as LSD, 2C-E, DOC, and AMT. However, they can also occur under the influence of deliriants and certain GABAergic depressants such as GHB and phenibut.