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4-HO-PiPT

This article is a stubmissing:
Dosage & Duration
Subjective Effects
Pharmacology
Tolerance
Harm Potential
History & Culture
Legality
4-HO-PiPT molecule structure4-HO-PiPT molecule structure
4-Hydroxy-N-propyl-N-isopropyltryptamine
Piprocin
Psychoactive Class
Psychedelic
Chemical Class
Tryptamine

Dosage & Duration

Dosage & Duration not written up yet

Subjective Effects

Subjective Effects not written up yet

Pharmacology

Pharmacology not written up yet

Interactions

Dangerous

Highest risk

These combinations are considered extremely harmful and should always be avoided. Reactions to these drugs taken in combination are highly unpredictable and have a potential to cause death.

Lithium

Unsafe

Avoid

There is considerable risk of physical harm when taking these combinations, they should be avoided where possible.

Tramadol

Caution

Use caution

These combinations are not usually physically harmful, but may produce undesirable effects, such as physical discomfort or overstimulation. Extreme use may cause physical health issues. Synergistic effects may be unpredictable. Care should be taken when choosing to use this combination.

AmphetaminesCannabisCocaineDiphenhydramine
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Tolerance

Tolerance not written up yet

Harm Potential

Harm Potential not written up yet

History & Culture

History & Culture not written up yet

Legality

Legality not written up yet

References

Source Pages

  1. Erowid Experience: 'Alien Comfort' (26mg oral)
  2. Erowid Experience: 'Dazzled and Disoriented' (30mg oral)
  3. Erowid Experience: 'Pushing the Boundaries' (0.1-40mg intranasal)
  4. Erowid: Experience Reports - 4-HO-PiPT
  5. Isomer Design - PiHKAL/TiHKAL Explorer
  6. Wikipedia

Further Reading

  1. Banister et al. 2023 - Compounds Patent (5-HT2A receptor activity)
  2. British Columbia Centre on Substance Use 2022 - Drug Checking Report

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed — this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

Times are UTCNewest first

24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

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