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MT-45

This article is a stubmissing:
Subjective Effects
Pharmacology
Interactions
Tolerance
History & Culture
MT-45 molecule structureMT-45 molecule structure
Chemical Class

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold30 mg
Light30-45 mg
Moderate45-60 mg
Strong60+ mg

Duration

Onset30-45 minutes
After Effects2-3 hours
Total4-6 hours

Subjective Effects

Subjective Effects not written up yet

Reagent Testing

Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.

Marquis(MQ)
white → brown1
Mecke(ME)
white → yellow2 → orange2
Liebermann(LB)
white → orange3 → red2
Hofmann(HM)
white → orange1
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Pharmacology

Pharmacology not written up yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

Moderate

Although users often report disliking MT-45 and few describe sustained use, addiction can still occur. Some users may feel pushed to take additional doses before onset or during the comedown.

Toxicity

Auditory System

MT-45 produces auditory issues in what appears to be a far more reliable manner than other opioids, with reports of tinnitus and hearing loss; in documented overdose cases, some individuals experienced transient hearing loss while at least one case involved persistent bilateral hearing loss that remained problematic at two-week follow-up, suggesting potential for very long-lasting or permanent damage.

Integumentary System

Recreational use has been associated with unusual dermatological effects including hair depigmentation, alopecia, and skin and nail reactions such as dermatitis and Mees lines; these effects are not typically seen with other opioid agonists.

Ocular System

Recreational use has been associated with cataracts, an unusual side effect not typically seen with other opioid agonists.

History & Culture

History & Culture not written up yet

Legality

By Country

Illegal3
United States flagUnited StatesIllegal
Czech Republic flagCzech RepublicIllegal
United Kingdom flagUnited KingdomIllegal

References

Citations

  1. e-Sbírka open data: current consolidated Annex 3 table to Government Regulation No. 463/2013 Coll.. opendata.eselpoint.gov.cz (n.d.). https://opendata.eselpoint.gov.cz/esel-esb/pr%C3%A1vn%C3%AD-akt-fragment/12364394931
  2. e-Sbírka open data: heading of Annex 3 to Government Regulation No. 463/2013 Coll.. opendata.eselpoint.gov.cz (n.d.). https://opendata.eselpoint.gov.cz/esel-esb/pr%C3%A1vn%C3%AD-akt-fragment/3014611231
  3. e-Sbírka open data: Government Regulation No. 463/2013 Coll., § 1(c)(2). opendata.eselpoint.gov.cz (n.d.). https://opendata.eselpoint.gov.cz/esel-esb/pr%C3%A1vn%C3%AD-akt-fragment/84244311
  4. e-Sbírka open data: Act No. 167/1998 Coll., § 4. opendata.eselpoint.gov.cz (n.d.). https://opendata.eselpoint.gov.cz/esel-esb/pr%C3%A1vn%C3%AD-akt-fragment/39359631
  5. Misuse of Drugs Act 1971, Schedule 2 — Controlled Drugs. legislation.gov.uk (n.d.). https://www.legislation.gov.uk/ukpga/1971/38/schedule/21
  6. Home Office: List of most commonly encountered drugs currently controlled under the misuse of drugs legislation. gov.uk (n.d.). https://www.gov.uk/government/publications/controlled-drugs-list--2/list-of-most-commonly-encountered-drugs-currently-controlled-under-the-misuse-of-drugs-legislation1
  7. Misuse of Drugs Act 1971 (Amendment) Order 2015, article 3. legislation.gov.uk (n.d.). https://www.legislation.gov.uk/uksi/2015/215/article/3/made1
  8. Home Office Circular 003/2015: control of MT-45 and 4,4’-DMAR. gov.uk (n.d.). https://www.gov.uk/government/publications/circular-0032015-a-change-to-the-misuse-of-drugs-act-1971-control-of-mt-45-and-44-dmar1
  9. Misuse of Drugs Regulations 2001, Schedule 1. legislation.gov.uk (n.d.). https://www.legislation.gov.uk/uksi/2001/3998/schedule/11
  10. Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2015. legislation.gov.uk (n.d.). https://www.legislation.gov.uk/uksi/2015/231/made1

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed — this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

Times are UTCNewest first

24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

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