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Dosage & Duration
Dosage
Doses are population estimates that vary widely between individuals.
Duration
Subjective Effects
Pharmacology
Interactions
An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.
Tolerance
Harm Potential
Addiction & Dependence
Psychological
HighMephenaqualone is described as highly addictive and associated with significant abuse potential. Repeated exposure can quickly produce tolerance, prompting users to take larger amounts to obtain comparable effects.
Physical
HighPhysical dependence develops with prolonged use. Abrupt discontinuation can lead to withdrawal symptoms including increased anxiety, insomnia, and potential seizures, consistent with GABAergic substance withdrawal.
Toxicity
Overdose can cause respiratory depression, which may become life-threatening particularly when combined with other CNS depressants such as alcohol, opiates, or benzodiazepines.
Seizure Risk
Seizures may occur during withdrawal following abrupt discontinuation after prolonged use, consistent with the withdrawal profile of other GABAergic substances.
History & Culture
Legality
International
Legal status outside Germany is largely undocumented and may differ under local designer-drug or analog laws.
By Country
References
Citations
- Gesetz über den Verkehr mit Betäubungsmitteln (Betäubungsmittelgesetz — BtMG), § 1 Betäubungsmittel. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/btmg_1981/__1.html1
- Betäubungsmittelgesetz, Anlage I (zu § 1 Abs. 1) — nicht verkehrsfähige Betäubungsmittel. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/btmg_1981/anlage_i.html1
- Betäubungsmittelgesetz, Anlage II (zu § 1 Abs. 1) — verkehrsfähige, aber nicht verschreibungsfähige Betäubungsmittel. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/btmg_1981/anlage_ii.html1
- Betäubungsmittelgesetz, Anlage III (zu § 1 Abs. 1) — verkehrsfähige und verschreibungsfähige Betäubungsmittel. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/btmg_1981/anlage_iii.html1
- Siebenundzwanzigste Verordnung zur Änderung von Anlagen des Betäubungsmittelgesetzes, BGBl. 2026 I Nr. 150. recht.bund.de (n.d.). https://www.recht.bund.de/bgbl/1/2026/150/regelungstext.pdf?__blob=publicationFile&v=11
- Neue-psychoaktive-Stoffe-Gesetz (NpSG), current consolidated text. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/npsg/BJNR261510016.html1
- Neue-psychoaktive-Stoffe-Gesetz, Anlage 1. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/npsg/anlage_1.html1
- Neue-psychoaktive-Stoffe-Gesetz, Anlage 2. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/npsg/anlage_2.html1
- Arzneimittelverschreibungsverordnung (AMVV), current consolidated text and Anlage 1. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/amvv/BJNR363210005.html1
- Draft Decree amending Hungarian Decree No 78/2022 on controlled substances — Annex 2, row 390. technical-regulation-information-system.ec.europa.eu (n.d.). https://technical-regulation-information-system.ec.europa.eu/hr/notification/27647/text/D/EN1
Article Status
Step 1 · Automated synthesisAn autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.
- Step 2 · First-pass reviewPending
Not yet reviewed — this article is pending editorial review by Lyrea.
- Step 3 · Citation reviewPending
No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.
Recent changes7 human edits · latest
Times are UTCNewest first
24 January 2026
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
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