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MEM

This article is a stubmissing:
Subjective Effects
Pharmacology
Interactions
Tolerance
History & Culture
Legality
MEM molecule structureMEM molecule structure
2,5-Dimethoxy-4-ethoxyamphetamine
Psychoactive Class
PsychedelicStimulant

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold15 mg
Light15-25 mg
Moderate25-35 mg
Strong35-45 mg
Heavy45+ mg

Duration

After Effects1-12 hours
Total8-16 hours

Subjective Effects

Subjective Effects not written up yet

Pharmacology

Pharmacology not written up yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Toxicity

Lethal Dosage

Toxic levels in humans are not known for many related compounds, and only a few have been explored for animal LD50 values. No numeric LD50 is provided.

Psychosis Risk

Low

MEM is described as a rare psychedelic amphetamine with suspected high potency and long duration, and confusion is listed among reported side effects. Persistent psychosis is not established.

History & Culture

History & Culture not written up yet

Legality

Legality not written up yet

References

Source Pages

  1. Bluelight: MEM Thread
  2. Isomer Design (TiHKAL/PiHKAL)
  3. IsomerDesign: MEM
  4. PiHKAL #122: MEM
  5. Wikipedia
  6. Wikipedia: 2,5 Dimethoxy 4 ethoxyamphetamine
  7. Wikipedia: 2,5-Dimethoxy-4-ethoxyamphetamine

Further Reading

  1. Halberstadt et al. 2020 - Potency of Hallucinogens
  2. Hemanth et al. 2023 - 5-HT2 Receptor Binding
  3. Kolaczynska et al. 2019 - 4-Alkoxy Substituted Amphetamines
  4. Ray 2010 - Psychedelics and the Receptorome
  5. Wallach et al. 2023 - 5-HT2A Signaling Pathways

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed — this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

Times are UTCNewest first

24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

All changes to this article · Site-wide recent changes

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