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EPT
N-Ethyl-N-propyltryptamine
Ethylpropyltryptamine
hidden
EPT is an obscure synthetic psychedelic of the tryptamine classcitation needed, structurally related to DMT1, DET, and DPT. Its original synthesis date is unknown, with the compound first appearing on the research chemical market in 2016. Notably, EPT has no documentation in the scientific literature and appears to be entirely a product of clandestine drug design. Early reports characterize its effects as mild and indistinct compared to related base tryptamines, most closely resembling a less potent DPT.
Dosage & Duration
Dosage
Doses are population estimates that vary widely between individuals.
Threshold~50 mg
Light50-75 mg
Moderate75-90 mg
Strong90-110 mg
Heavy110+ mg
Duration
Onset20-60 minutes
After Effects1-6 hours
Total2-4 hours
Subjective Effects
Legacy content. A statistically backed ontology from Mindstate Design Labs is coming soon.
EPT is a rarely encountered psychedelic tryptamine, and its subjective effects remain sparsely documented. The limited anecdotal record describes a classic serotonergic psychedelic profile broadly in line with its close structural relatives such as DET and DPT, with visual alterations and a psychedelic headspace of relatively moderate character. Detailed phenomenological documentation has not yet been established for this compound.
Cognitive
The headspace is described as a characteristic psychedelic state, including mood elevation and an altered sense of the passage of time.
Visual
Visual effects are consistent with those of other psychedelic tryptamines, scaling with dose.
See also: Psychedelic Intensity Scale, Effects of psychedelics (visual, cognitive, miscellaneous)
Pharmacology
Pharmacodynamics
EPT is thought to act principally as a partial agonist at the serotonin 5-HT2A receptor, which is believed to underlie its psychedelic effects.citation needed Like other serotonergic tryptamines, EPT shares strong structural similarity with serotonin itself, which contributes to its affinity for 5-HT receptor sites.
Pharmacokinetics
The pharmacological profile of EPT has not been studied and the metabolism of EPT is unknown.
Metabolitesnone documented yet
Interactions
Interactions not written up yet
An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.
Tolerance
Tolerance timelines are rules of thumb, not exact schedules, and vary widely between individuals and use patterns.
Full Tolerance
EPT differs from DMT in that tolerance appears to emerge almost immediately after ingestion.
Baseline Reset
Approximately 7 days without further consumption
Half Tolerance
Approximately 3 days
Cross Tolerance
Psychedelics
Harm Potential
Addiction & Dependence
Psychological
Extremely LowAnecdotal reports suggest EPT has low abuse potential and does not produce dependence, similar to other unsubstituted tryptamines such as DMT, DET, and MET.
Physical
Extremely LowAnecdotal reports suggest EPT does not produce physical dependence.
History & Culture
EPT's original synthesis date remains unknown. The compound first appeared for sale on the online research chemical market in 2016, emerging as what appears to be an entirely novel product of clandestine drug design rather than a compound derived from academic or pharmaceutical research. Unlike…
Legality
International
EPT is not listed in the inspected current schedules of the 1971 Convention on Psychotropic Substances; its status under the 1961 and 1988 conventions remains a research gap.
By Country
Illegal9
ArgentinaIllegal (analog/blanket ban)Argentina treats substances falling within the chemical groups in Annex II of Decree 560/2019 as estupefacientes. Annex II defines the triptamine group broadly and permits each of the two amine substituents to be a linear, branched, or cyclic C1–8 alkyl or alkenyl group; EPT's N-ethyl and N-propyl substituents fit those terms. The annex also covers relevant stereoisomers and salts.
BelgiumIllegal (analog/blanket ban)Arrêté royal du 6 septembre 2017 réglementant les substances stupéfiantes et psychotropes, annexe IVa8910
EPT (N-ethyl-N-propyltryptamine) falls within Annex IVa's generic tryptamine-derivative definition. The definition covers 2-(1H-indol-3-yl)ethanamine bearing C1–C5 alkyl groups at both amine substituent positions, with hydrogen permitted at the ring and alpha positions; EPT's ethyl and propyl groups match those parameters. Belgium therefore controls EPT by generic structural coverage rather than requiring it to be named individually.
DenmarkIllegal (analog/blanket ban)Bekendtgørelse om euforiserende stoffer, BEK nr. 405 af 26/03/202611
EPT is covered by the generic tryptamine-group entry on List B because it is structurally derived from tryptamine by ethyl and propyl substitution on the side-chain nitrogen. List B substances may be used only for medical and scientific purposes, and possession and other handling are subject to the decree's authorization regime.
IrelandIllegal (analog/blanket ban)Misuse of Drugs Act 1977 (Controlled Drugs) (Designation) Order 2022 (S.I. No. 211/2022)16
EPT (N-ethyl-N-propyltryptamine) falls within Schedule 1's generic coverage of substances structurally derived from tryptamine by side-chain nitrogen substitution with one or more alkyl substituents and no other substituent. The Order designates Schedule 1 drugs under section 13(1) of the Misuse of Drugs Act 1977, making manufacture, production, preparation, sale, supply, distribution and possession unlawful except for licensed research or other specified special purposes.
ItalyIllegalDecreto del Ministro della salute 11 agosto 2020, aggiornamento delle tabelle del D.P.R. 9 ottobre 1990, n. 3094
Listed as a controlled substance under Tabella I of Italian drug legislation. Possession, production, and distribution are prohibited.
NorwayIllegalNorway's current narkotikalisten names Etylpropyltryptamin and identifies it chemically as N-etyl-N-propyl-1H-indol-3-etanamin (with a second synonymous systematic name). The substance was added by the 26 September 2024 amending regulation and is designated prohibited under § 5.
SingaporeIllegal (analog/blanket ban)EPT (N-ethyl-N-propyltryptamine) falls within the First Schedule's generic tryptamine definition because it is structurally derived from tryptamine by alkyl substitution at the side-chain nitrogen. The schedule classifies this generic group as Class A controlled drugs and expressly includes ethers, salts, stereoisomers, preparations, and products containing covered compounds. EPT is covered by the generic definition rather than named as an example; the schedule does expressly name its 5-methoxy derivative, 5-MeO-EPT.
South AfricaIllegal (analog/blanket ban)Drugs and Drug Trafficking Act 140 of 1992, Schedule 2 Part III23
Schedule 2 Part III expressly lists diethyltryptamine and dimethyltryptamine as undesirable dependence-producing substances. Its coverage clause also includes all homologues of listed substances, defined as chemically related substances incorporating a similar structural fragment or exhibiting similar pharmacodynamic properties; EPT (N-ethyl-N-propyltryptamine) is therefore covered as a homologue rather than by exact name.
United KingdomIllegalMisuse of Drugs Act 1971, Schedule 2, Part I, paragraph 1(b)25
Controlled under the Misuse of Drugs Act 1971 as a result of the tryptamine catch-all clause,25 which encompasses tryptamine derivatives regardless of individual scheduling. Class A substances carry the most severe penalties, including up to 7 years imprisonment for possession and life imprisonment for supply.
Controlled / restricted2
GermanyRestrictedRegulated under the Neue-psychoaktive-Stoffe-Gesetz (New Psychoactive Substances Act) since July 18, 2019.15 Production, import with intent to distribute, administration to others, and trading are criminal offenses. Personal possession is prohibited but not subject to criminal penalties.
SwitzerlandRestrictedBetäubungsmittelverzeichnisverordnung (BetmVV-EDI), standing 13 March 202622
This is generic structural coverage, not an express EPT name listing.
Not scheduled1
United StatesUnscheduledNot specifically scheduled under federal law. However, due to structural similarity to DMT (a Schedule I substance), it may be subject to prosecution under the Federal Analogue Act24 if sold for human consumption or used for illicit purposes. Legal status may vary by state.citation needed
References
Source Pages
Citations
- Chadeayne AR, Pham DNK, Golen JA, & Manke DR. (2020). DMT analogues: N-ethyl-N-propyltryptamine and N-allyl-N-methyltryptamine as their hydrofumarate salts. Acta Crystallographica Section E: Crystallographic Communications, 76(8), 1201–1205. https://doi.org/10.1107/s20569890200086831
- Tanaka R, Kawamura M, Hakamatsuka T, & Kikura-Hanajiri R. (2021). Identification of six tryptamine derivatives as designer drugs in illegal products. Forensic Toxicology, 39, 248–258. https://doi.org/10.1007/s11419-020-00556-51
- Bergh MS-S, Bogen IL, Grafinger KE, Huestis MA, & Øiestad AML. (2024). Metabolite markers for three synthetic tryptamines N-ethyl-N-propyltryptamine, 4-hydroxy-N-ethyl-N-propyltryptamine, and 5-methoxy-N-ethyl-N-propyltryptamine. Drug Testing and Analysis. https://doi.org/10.1002/dta.36681
- Decreto del Ministro della salute 11 agosto 2020, aggiornamento delle tabelle del D.P.R. 9 ottobre 1990, n. 309. gazzettaufficiale.it (n.d.). https://www.gazzettaufficiale.it/atto/vediMenuHTML?atto.codiceRedazionale=20A04540&atto.dataPubblicazioneGazzetta=2020-08-21&tipoSerie=serie_generale&tipoVigenza=originario1
- Forskrift om narkotika (narkotikaforskriften), FOR-2013-02-14-199, narkotikalisten and § 5. lovdata.no (n.d.). https://lovdata.no/dokument/SF/forskrift/2013-02-14-199/KAPITTEL_1-11
- Forskrift om narkotika (narkotikaforskriften), FOR-2013-02-14-199, narkotikalisten and § 5. lovdata.no (n.d.). https://lovdata.no/LTI/forskrift/2024-09-26-23011
- Forskrift om narkotika (narkotikaforskriften), FOR-2013-02-14-199, narkotikalisten and § 5. dmp.no (n.d.). https://www.dmp.no/tilvirkning-import-og-salg/narkotika-og-doping/narkotikalisten1
- Arrêté royal du 6 septembre 2017 réglementant les substances stupéfiantes et psychotropes, annexe IVa. afmps.be (n.d.). https://www.afmps.be/sites/default/files/content/INSP/NARC/annex%20IV_non%20official%20consolidated%20version.pdf1
- Arrêté royal du 6 septembre 2017 réglementant les substances stupéfiantes et psychotropes, annexe IVa. news.belgium.be (n.d.). https://news.belgium.be/sites/default/files/legacy/media/source78420/2017_09_26_AR_Stupefiants_et_substances_psychotropes_DEF.pdf1
- Arrêté royal du 6 septembre 2017 réglementant les substances stupéfiantes et psychotropes, annexe IVa. afmps.be (n.d.). https://www.afmps.be/fr/humain/produits_particuliers/subst_specialement_reglementees/stupefiants_et_psychotropes/substances1
Further Reading
Article Status
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Recent changes8 human edits · latest
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19 August 2026
24 January 2026
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
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