WARNINGMIXING OR WITHDRAWAL CAN BE DANGEROUS
Ordinary doses in combination with other depressants can fatally stop breathing. After prolonged dependency, stopping suddenly can also cause seizures or delirium; seek medical help.
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Dosage & Duration
Dosage
Doses are population estimates that vary widely between individuals.
Duration
Subjective Effects
Pharmacology
Interactions
An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.
Tolerance
Harm Potential
Addiction & Dependence
Psychological
HighClotiazepam is a recognised drug of abuse and is classified as habit-forming. As a thienodiazepine with benzodiazepine-like activity, it carries significant psychological dependence potential with regular use.
Physical
HighPhysical dependence develops with chronic use, consistent with other benzodiazepine-class substances. Withdrawal syndrome may occur upon discontinuation.
Toxicity
Reversible hepatitis has been described in association with clotiazepam.
History & Culture
Legality
By Country
References
Citations
- Controlled Drugs and Substances Act — Schedule IV. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/c-38.8/page-12.html1
- Controlled Drugs and Substances Act — sections 4 and 5. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-1.html1
- Controlled Drugs and Substances Act — sections 6 and 7. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-2.html1
- Controlled Drugs and Substances Act — coming into force. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-8.html1
- List of most commonly encountered drugs currently controlled under the misuse of drugs legislation. gov.uk (n.d.). https://www.gov.uk/government/publications/controlled-drugs-list--2/list-of-most-commonly-encountered-drugs-currently-controlled-under-the-misuse-of-drugs-legislation1
- Misuse of Drugs Act 1971, Schedule 2 Part III paragraph 1 (latest revised text). legislation.gov.uk (n.d.). https://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/III/paragraph/11
- The Misuse of Drugs Regulations 2001, Schedule 4 (latest revised text). legislation.gov.uk (n.d.). https://www.legislation.gov.uk/uksi/2001/3998/schedule/41
- The Misuse of Drugs Act 1971 (Modification) Order 1985. legislation.gov.uk (n.d.). https://www.legislation.gov.uk/uksi/1985/1995/made1
- Misuse of Drugs Act 1971, section 5 (latest revised text). legislation.gov.uk (n.d.). https://www.legislation.gov.uk/ukpga/1971/38/section/51
- Ethylbromazolam: a review of the evidence on its use and harms (accessible version). gov.uk (n.d.). https://www.gov.uk/government/publications/ethylbromazolam-review-of-the-evidence-on-its-use-and-harms/ethylbromazolam-a-review-of-the-evidence-on-its-use-and-harms-accessible-version1
Article Status
Step 1 · Automated synthesisAn autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.
- Step 2 · First-pass reviewPending
Not yet reviewed — this article is pending editorial review by Lyrea.
- Step 3 · Citation reviewPending
No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.
Recent changes7 human edits · latest
Times are UTCNewest first
24 January 2026
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
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