Skip to main content
Lyrea avatar

Not yet reviewed — this article is pending editorial review by Lyrea.

Citation noticeOur citation system is being overhauled

References and citation markers may currently be incomplete, mismatched, or incorrect. This system is being rebuilt and reviewed before the full site launch.

Clotiazepam

This article is a stubmissing:
Subjective Effects
Pharmacology
Interactions
Tolerance
History & Culture
Clotiazepam molecule structureClotiazepam molecule structure
Chemical Class

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold~2.5 mg
Light2.5-5 mg
Moderate5-10 mg
Strong10-15 mg
Heavy15+ mg

Duration

Onset10-30 minutes
After Effects4-8 hours
Total4-8 hours

Subjective Effects

Subjective Effects not written up yet

Pharmacology

Pharmacology not written up yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

High

Clotiazepam is a recognised drug of abuse and is classified as habit-forming. As a thienodiazepine with benzodiazepine-like activity, it carries significant psychological dependence potential with regular use.

Physical

High

Physical dependence develops with chronic use, consistent with other benzodiazepine-class substances. Withdrawal syndrome may occur upon discontinuation.

Toxicity

Hepatic

Reversible hepatitis has been described in association with clotiazepam.

History & Culture

History & Culture not written up yet

Legality

By Country

Illegal2
United States flagUnited StatesIllegal
United Kingdom flagUnited KingdomIllegal
Controlled / restricted1
Canada flagCanadaRestricted

References

Citations

  1. Controlled Drugs and Substances Act — Schedule IV. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/c-38.8/page-12.html1
  2. Controlled Drugs and Substances Act — sections 4 and 5. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-1.html1
  3. Controlled Drugs and Substances Act — sections 6 and 7. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-2.html1
  4. Controlled Drugs and Substances Act — coming into force. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-8.html1
  5. List of most commonly encountered drugs currently controlled under the misuse of drugs legislation. gov.uk (n.d.). https://www.gov.uk/government/publications/controlled-drugs-list--2/list-of-most-commonly-encountered-drugs-currently-controlled-under-the-misuse-of-drugs-legislation1
  6. Misuse of Drugs Act 1971, Schedule 2 Part III paragraph 1 (latest revised text). legislation.gov.uk (n.d.). https://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/III/paragraph/11
  7. The Misuse of Drugs Regulations 2001, Schedule 4 (latest revised text). legislation.gov.uk (n.d.). https://www.legislation.gov.uk/uksi/2001/3998/schedule/41
  8. The Misuse of Drugs Act 1971 (Modification) Order 1985. legislation.gov.uk (n.d.). https://www.legislation.gov.uk/uksi/1985/1995/made1
  9. Misuse of Drugs Act 1971, section 5 (latest revised text). legislation.gov.uk (n.d.). https://www.legislation.gov.uk/ukpga/1971/38/section/51
  10. Ethylbromazolam: a review of the evidence on its use and harms (accessible version). gov.uk (n.d.). https://www.gov.uk/government/publications/ethylbromazolam-review-of-the-evidence-on-its-use-and-harms/ethylbromazolam-a-review-of-the-evidence-on-its-use-and-harms-accessible-version1

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed — this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

Times are UTCNewest first

24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

All changes to this article · Site-wide recent changes

Suggest an edit

Spotted a mistake, an outdated claim, or something missing from the Clotiazepam article? Send the editors a private note. Feedback lands in a moderation queue and is never shown on the site.

Wish to give generalised feedback? You can do so here.