Not yet reviewed — this article is pending editorial review by Lyrea.

WARNINGMIXING OR WITHDRAWAL CAN BE DANGEROUS

Ordinary doses in combination with other depressants can fatally stop breathing. After prolonged dependency, stopping suddenly can also cause seizures or delirium; seek medical help.

Citation noticeOur citation system is being overhauled

References and citation markers may currently be incomplete, mismatched, or incorrect. This system is being rebuilt and reviewed before the full site launch.

Cloniprazepam

This article is a stubmissing:

Pharmacology

Interactions

Tolerance

History & Culture

Legality

Chemical Class

1,4-Benzodiazepine

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold~0.5 mg

Light0.5-1 mg

Moderate1-2 mg

Strong2-4 mg

Heavy4+ mg

Duration

Onset15-45 minutes

After Effects1-8 hours

Total6-9 hours

Subjective Effects

Legacy content. A statistically backed ontology from Mindstate Design Labs is coming soon.

Effects vary widely by individual, dose, and context.

Physical

The physical effects of cloniprazepam can be broken down into several components which progressively intensify proportional to dosage.

Dizziness Muscle relaxation Physical euphoria Motor control loss Respiratory depression Seizure suppression

Cognitive

The cognitive effects of cloniprazepam can be broken down into several components which progressively intensify proportional to dosage. The general head space of cloniprazepam is described by many as one of intense relaxation, anxiety suppression and decreased inhibition. It contains a large number of typical depressant cognitive effects. Paradoxical reactions to benzodiazepines such as increased seizures (in epileptics), aggression, increased anxiety, violent behavior, loss of impulse control, irritability and suicidal behavior sometimes occur (although they are rare in the general population, with an incidence rate below 1%). These paradoxical effects occur with greater frequency in recreational abusers, individuals with mental disorders, children, and patients on high-dosage regimes.

Amnesia Anxiety suppression Thought deceleration Disinhibition Information processing suppression Euphoria Compulsive redosing

Adapted from the Clonazepam subjective effects documentation. Cloniprazepam is a prodrug of clonazepam and is reported to produce an effectively identical experience. Forked from Subjective Effect Documentation by

Josie Kins September 2015.

Reagent Testing

Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.

Marquis(MQ)

Mecke(ME)

Liebermann(LB)

Froe(FR)

PROtestkit.eu

Pharmacology

Pharmacology not written up yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check

TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

High

Classified as habit-forming. As a prodrug for clonazepam, it carries significant psychological addiction potential typical of benzodiazepines.

Physical

High

Physical dependence develops with regular use. Abrupt discontinuation can cause life-threatening withdrawal symptoms including seizures.

History & Culture

History & Culture not written up yet

Legality

Legality not written up yet

Article Status

Step 1 · Automated synthesis
An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.
Step 2 · First-pass reviewPending
Not yet reviewed — this article is pending editorial review by Lyrea.
Step 3 · Citation reviewPending
No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest 24 Jan

Times are UTCNewest first

24 January 2026

23:32
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
23:25
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
23:20
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
23:15
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
22:57
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
22:42
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
22:21
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

All changes to this article · Site-wide recent changes

Suggest an edit

Spotted a mistake, an outdated claim, or something missing from the Cloniprazepam article? Send the editors a private note. Feedback lands in a moderation queue and is never shown on the site.

Wish to give generalised feedback? You can do so here.