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4f-MPH

This article is a stubmissing:
Subjective Effects
Pharmacology
Interactions
Tolerance
History & Culture
4f-MPH molecule structure4f-MPH molecule structure
Chemical Class

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold5 mg
Light5-10 mg
Moderate10-15 mg
Strong15-20 mg
Heavy20+ mg

Duration

Onset30-60 minutes
Peak2-4 hours
Offset1-2 hours
After Effects5-10 hours
Total4-8 hours

Subjective Effects

Subjective Effects not written up yet

Reagent Testing

Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.

Mandelin(MD)
yellow2 → orange2
Liebermann(LB)
white → yellow1
Morr(MO)
pink2 → green1
Simons(SI)
orange1 → blue2
Powered by PROtestkit.eu

Pharmacology

Pharmacology not written up yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

High

4F-MPH has abuse potential on par with amphetamine or MDMA due to its euphoric effects and action upon dopamine transporters. Some users have become addicted to this substance, and compulsive redosing is reported, particularly at high doses or with non-oral routes of administration.

Toxicity

Cardiovascular

Acute cardiovascular effects including abnormal heartbeat and vasoconstriction occur during use; excessive stimulation may result in dangerous increases in blood pressure and heart strain, particularly at higher doses or in combination with other stimulants.

Psychosis Risk

Risk of delusions, mania, and psychosis has been noted, particularly when combined with dissociatives. The substance may carry inherent psychosis risk at higher doses.

Seizure Risk

Seizures have been mentioned as a potential risk in extreme cases, particularly in combination with certain other substances.

History & Culture

History & Culture not written up yet

Legality

By Country

Illegal4
Germany flagGermanyIllegal (analog/blanket ban)
Switzerland flagSwitzerlandIllegal
Turkey flagTurkeyIllegal
United Kingdom flagUnited KingdomIllegal
Controlled / restricted1
United States flagUnited StatesRestricted
Legal / decriminalized1
Italy flagItalyDecriminalized

References

Citations

  1. Neue-psychoaktive-Stoffe-Gesetz (NpSG), consolidated text. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/npsg/BJNR261510016.html1
  2. PubChem PUG REST compound record for 4-fluoromethylphenidate. pubchem.ncbi.nlm.nih.gov (n.d.). https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/name/4-fluoromethylphenidate/property/IUPACName,MolecularFormula,MolecularWeight,CanonicalSMILES,InChIKey/JSON1
  3. NpSG Anlage 1, preliminary provisions and Nummer 1. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/npsg/anlage_1.html1
  4. NpSG section 2, definitions. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/npsg/__2.html1
  5. NpSG section 3, unauthorized handling. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/npsg/__3.html1
  6. NpSG section 4, criminal provisions. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/npsg/__4.html1
  7. NpSG section 1, scope. gesetze-im-internet.de (n.d.). https://www.gesetze-im-internet.de/npsg/__1.html1
  8. Ministero della Salute — Tabelle delle sostanze stupefacenti e psicotrope, Tabelle allegate al Testo unico. salute.gov.it (n.d.). https://www.salute.gov.it/new/it/tema/medicinali-stupefacenti-e-precursori-di-droghe/tabelle-delle-sostanze-stupefacenti-e/?paragraph=01
  9. Ministero della Salute — TABELLA I, current schedule updated through D.M. 28 aprile 2026. salute.gov.it (n.d.). https://www.salute.gov.it/new/sites/default/files/TABELLA%20I%20DM%2028%20Aprile%202026.xlsx1
  10. Ministero della Salute, Decreto 5 ottobre 2021 — Inserimento nella tabella I di nuove sostanze psicoattive (21A06118). gazzettaufficiale.it (n.d.). https://www.gazzettaufficiale.it/atto/vediMenuHTML?atto.codiceRedazionale=21A06118&atto.dataPubblicazioneGazzetta=2021-10-18&tipoSerie=serie_generale&tipoVigenza=originario1

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed — this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

Times are UTCNewest first

24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

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