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Dosage & Duration
Dosage
Doses are population estimates that vary widely between individuals.
Duration
Subjective Effects
Pharmacology
Interactions
An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.
Tolerance
Harm Potential
Addiction & Dependence
Psychological
HighAnimal studies indicate abuse potential comparable to cocaine and amphetamine, suggesting a significant risk of psychological dependence and compulsive patterns of use.
Toxicity
One reported fatality involved blood concentrations of 21.3 mg/L with concurrent diazepam use. Doses above 15-20mg are considered dangerous.
LD50 Data
| Species | Route | Value |
|---|---|---|
| mouse | oral | 17 mg/kg |
Pulmonary hypertension has been associated with 4-methylaminorex use, similar to the related appetite suppressant aminorex which caused an epidemic of pulmonary hypertension.
High doses in animal studies caused reduction in tryptophan hydroxylase activity, a possible marker for serotonin neurotoxicity; the highest doses tested caused clonic seizures and some deaths in rats.
Seizure Risk
High doses have caused clonic seizures in rat studies, with some fatalities occurring at the highest doses tested (20 mg/kg).
History & Culture
Legality
Article Status
Step 1 · Automated synthesisAn autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.
- Step 2 · First-pass reviewPending
Not yet reviewed — this article is pending editorial review by Lyrea.
- Step 3 · Citation reviewPending
No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.
Recent changes7 human edits · latest
Times are UTCNewest first
24 January 2026
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
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