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4-Benzylpiperidine

This article is a stubmissing:
Subjective Effects
Pharmacology
Interactions
Tolerance
History & Culture
Legality
4-Benzylpiperidine molecule structure4-Benzylpiperidine molecule structure
4-PMPD
Psychoactive Class
Stimulant
Chemical Class
PiperidineBenzylpiperidine

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold~75 mg
Light75-125 mg
Moderate125-200 mg
Strong200-350 mg
Heavy350+ mg

Duration

Onset10-45 minutes
Total2-5 hours

Subjective Effects

Subjective Effects not written up yet

Pharmacology

Pharmacology not written up yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

Described as habit-forming, suggesting some potential for psychological dependence, though human use data is limited.

Toxicity

Lethal Dosage

Potentially dangerous in overdose given the combination of MAOI and monoamine releasing properties.

Psychosis Risk

Visual and auditory hallucinations have been reported as adverse effects.

History & Culture

History & Culture not written up yet

Legality

Legality not written up yet

References

Source Pages

  1. Bluelight: 4-Benzylpiperidine user experiences megathread
  2. Wikipedia

Further Reading

  1. Biosynth - MAO-A/B IC50 values
  2. ChemicalBook - Onset, duration and discrimination study summary
  3. Drugs-Forum: 4-PMPD experience report and theory
  4. Reddit: r/Nootropics - 4-Benzylpiperidine user experiences
  5. Reddit: r/Nootropics - 4-PMPD discussion thread
  6. ScienceDirect: Structural requirements for modulating 4-benzylpiperidine uptake (SAR)
  7. ScienceDirect: Transdermal formulation study showing rapid onset and short duration
  8. Sigma-Aldrich - Dopamine-selective releaser product sheet

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed — this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

Times are UTCNewest first

24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

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