Valerylfentanyl
Valerylfentanyl is a synthetic opioid and depressant of the fentanyl analogue family. It is a higher homologue of butyrfentanyl, though it exhibits greatly reduced potency compared to its parent compound. Classified as a research chemical, valerylfentanyl carries the risks common to synthetic opioids, including habit-forming potential and the danger of respiratory depression associated with this class of substances.
Contents
Dosage & Duration
Dosage
Subjective Effects
Documented subjective effects are limited to reported side effects shared with fentanyl and its other analogs, with no detailed accounts of the experience itself available. Reported effects include itching and nausea, alongside respiratory depression that may become life-threatening.
Reagent Testing
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Pharmacology
Pharmacodynamics
Valerylfentanyl is an opioid analgesic and a structural analog of fentanyl, representing a higher homologue of butyrfentanyl. In mice, it fully substituted for oxycodone and produced antinociception with a potency comparable to morphine, consistent with activity at μ-opioid receptors. It notably failed to stimulate locomotor activity in mice at doses up to 100 mg/kg.
Pharmacokinetics
Tolerance
Opioids (fentanyl, morphine, oxycodone, heroin, and other μ-opioid receptor agonists)
Harm Potential
Addiction & Dependence
Psychological
Classified as habit-forming.
Toxicity
As a fentanyl analog, valerylfentanyl shares the side-effect profile of fentanyl, including potentially serious and life-threatening respiratory depression. Fentanyl analogs as a class have been responsible for hundreds of overdose deaths across Europe, the former Soviet republics, and the United States.
Potentially serious respiratory depression can occur, which may be life-threatening and is the primary cause of overdose fatalities associated with fentanyl analogues.
History & Culture
Valerylfentanyl is an opioid analgesic belonging to the fentanyl analog class of designer drugs. It has appeared on online drug markets, though it remains one of the less commonly encountered fentanyl derivatives with limited documentation in the scientific and illicit drug monitoring literature.…
Legality
International
UNODC Schedule I recommendation announced in December 2019
By Country
Automated synthesisInformation aggregated and synthesized using an autonomous workflow built by Josie Kins.
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