WARNINGMIXING OR WITHDRAWAL CAN BE DANGEROUS
Ordinary doses in combination with other depressants can fatally stop breathing. After prolonged dependency, stopping suddenly can also cause seizures or delirium; seek medical help.
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Dosage & Duration
Dosage
Doses are population estimates that vary widely between individuals.
Duration
Subjective Effects
Pharmacology
Interactions
An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.
Tolerance
Harm Potential
Addiction & Dependence
Psychological
HighQuazepam is described as habit-forming and as a drug with misuse potential; boxed-warning language covers abuse, misuse, and addiction across benzodiazepines.
Physical
HighBenzodiazepine physical dependence and withdrawal are described, and quazepam should be withdrawn gradually after use beyond four weeks to avoid severe withdrawal syndrome.
Toxicity
Overdose may cause drowsiness, dysarthria, confusion, ataxia, coma, paradoxical disinhibition, and next-day impairment from metabolite accumulation.
Severe overdose may lead to respiratory depression.
Repeated administration and active metabolite accumulation are associated with balance impairment, unstable posture, motor incoordination, and fall risk.
Special precaution is advised in pregnancy, and quazepam and active metabolites are excreted into breast milk.
Seizure Risk
Flumazenil can provoke seizures in long-term benzodiazepine users with physical dependency, and abrupt withdrawal in animal studies caused convulsions and withdrawal-related deaths.
History & Culture
Legality
International
Quazepam has approved and illicit regulatory groupings.
By Country
References
Citations
- 21 C.F.R. § 1308.14 — Schedule IV. ecfr.gov (n.d.). https://www.ecfr.gov/api/renderer/v1/content/enhanced/current/title-21?part=1308§ion=1308.141
- DEA Controlled Substances—Alphabetical Order (27-Aug-26). deadiversion.usdoj.gov (n.d.). https://www.deadiversion.usdoj.gov/schedules/orangebook/c_cs_alpha.pdf1
- DEA Scheduling Actions—Chronological Order (27-Aug-26). deadiversion.usdoj.gov (n.d.). https://www.deadiversion.usdoj.gov/schedules/orangebook/b_sched_chron.pdf1
- DailyMed — QUAZEPAM tablet. dailymed.nlm.nih.gov (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f7d63f3f-5303-48ab-bce2-35fd62c457991
- openFDA Drugs@FDA record — Quazepam (NDA018708). api.fda.gov (n.d.). https://api.fda.gov/drug/drugsfda.json?search=application_number%3A%22NDA018708%221
- 21 U.S.C. § 829 — Prescriptions. uscode.house.gov (n.d.). https://uscode.house.gov/view.xhtml?req=granuleid%3AUSC-prelim-title21-section829&num=0&edition=prelim1
- 21 U.S.C. § 841 — Prohibited acts A. uscode.house.gov (n.d.). https://uscode.house.gov/view.xhtml?req=granuleid%3AUSC-prelim-title21-section841&num=0&edition=prelim1
- 21 U.S.C. § 844 — Penalties for simple possession. uscode.house.gov (n.d.). https://uscode.house.gov/view.xhtml?req=granuleid%3AUSC-prelim-title21-section844&num=0&edition=prelim1
Article Status
Step 1 · Automated synthesisAn autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.
- Step 2 · First-pass reviewPending
Not yet reviewed — this article is pending editorial review by Lyrea.
- Step 3 · Citation reviewPending
No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.
Recent changes7 human edits · latest
Times are UTCNewest first
24 January 2026
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
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