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Dosage & Duration
Dosage
Doses are population estimates that vary widely between individuals.
Duration
Subjective Effects
Pharmacology
Interactions
An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.
Tolerance
Harm Potential
Addiction & Dependence
Physical
Extremely LowOnly a single case report of temporary depressive symptoms after discontinuation is quoted; broader dependence is not supported.
Toxicity
Rare serious complications include heart attack, hemorrhagic stroke, coronary vasospasm, sudden death, tachycardia, palpitations, arrhythmias, hypertension, and hypertensive crisis with MAOIs.
CNS stimulation, insomnia, restlessness, excitability, dizziness, anxiety, hallucinations, tremors, convulsions, and coma are described in adverse-effect or overdose contexts.
Ischemic colitis is listed as a rare adverse effect.
Listed rare severe dermatologic reactions include non-pigmenting fixed drug eruption, systemic contact dermatitis, and recurrent pseudo-scarlatina.
Psychosis Risk
Pseudoephedrine, particularly with other drugs including narcotics, may contribute to episodes of psychosis.
Seizure Risk
Convulsions are listed among overdose symptoms and seizures are described as a rare therapy-associated adverse effect.
History & Culture
Legality
International
Pseudoephedrine is widely sold as a decongestant.
Article Status
Step 1 · Automated synthesisAn autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.
- Step 2 · First-pass reviewPending
Not yet reviewed — this article is pending editorial review by Lyrea.
- Step 3 · Citation reviewPending
No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.
Recent changes7 human edits · latest
Times are UTCNewest first
24 January 2026
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
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