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Pentazocine

This article is a stubmissing:
Subjective Effects
Pharmacology
Interactions
Tolerance
History & Culture
Pentazocine molecule structurePentazocine molecule structure

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold~10 mg
Light10-20 mg
Strong30-60 mg
Heavy60+ mg

Subjective Effects

Subjective Effects not written up yet

Reagent Testing

Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.

Mandelin(MD)
yellow2 → green2
Froe(FR)
white → blue2
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Pharmacology

Pharmacology not written up yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

Moderate

Pentazocine is considered a habit-forming opioid depressant.

Toxicity

respiratory and central nervous system

Pentazocine shares opioid adverse effects including drowsiness and respiratory depression; CNS depression can increase with other depressants.

psychiatric and neurologic

Hallucinations, nightmares, delusions, and psychotomimetic effects are described as relatively frequent compared with many opioids.

cardiovascular

At high doses, pentazocine can raise blood pressure or heart rate, and intravenous administration after myocardial infarction may add cardiac workload.

injection site and immune/skin

Multiple injections have caused severe injection-site necrosis and sepsis, sometimes requiring amputation; rare agranulocytosis, erythema multiforme, and toxic epidermal necrolysis are also reported.

Psychosis Risk

Pentazocine is described as fairly frequently causing hallucinations, nightmares, delusions, and psychotomimetic effects.

Seizure Risk

Pentazocine is among agents that reduce seizure threshold, but seizure frequency is not quantified.

History & Culture

History & Culture not written up yet

Legality

International

Pentazocine is approved and vet approved.

By Country

Illegal2
United States flagUnited StatesIllegal
Canada flagCanadaIllegal

References

Citations

  1. Controlled Drugs and Substances Act — Schedule I. laws-lois.justice.gc.ca (n.d.). https://www.laws-lois.justice.gc.ca/eng/acts/C-38.8/section-sched95314.html1
  2. Controlled Drugs and Substances Act — section 4. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/section-4.html1
  3. Controlled Drugs and Substances Act — section 5. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/section-5.html1
  4. Controlled Drugs and Substances Act — section 6. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/section-6.html1
  5. Controlled Drugs and Substances Act — section 7. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/section-7.html1
  6. Controlled Drugs and Substances Act — Coming into Force. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-8.html1
  7. Narcotic Control Regulations — Schedule. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/regulations/C.R.C.%2C_c._1041/FullText.html1
  8. Health Canada Drug Product Database — TALWIN tablet. health-products.canada.ca (n.d.). https://health-products.canada.ca/dpd-bdpp/info?code=18230&lang=eng1
  9. Health Canada Drug Product Database — pentazocine lactate search results. health-products.canada.ca (n.d.). https://health-products.canada.ca/dpd-bdpp/search-fast-recherche-rapide?lang=eng&no=01088520011
  10. 21 C.F.R. § 1308.14 — Schedule IV. ecfr.gov (n.d.). https://www.ecfr.gov/api/renderer/v1/content/enhanced/current/title-21?part=1308&section=1308.141

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed — this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

Times are UTCNewest first

24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

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