N-Ethylhexedrone

N-Ethylhexedrone is permanently listed in federal Schedule I. The current listing expressly identifies N-ethylhexedrone as alpha-ethylaminohexanophenone and 2-(ethylamino)-1-phenylhexan-1-one, with DEA number 7246. Schedule I controls and associated administrative, civil, and criminal sanctions apply to handling or proposed handling, including manufacture, distribution, reverse distribution, import, export, research, instructional activities, chemical analysis, and possession. The June 1, 2022 final rule permanently replaced the prior temporary Schedule I control.

N-ethylhexedrone (2-(ethylamino)-1-phenylhexan-1-one) is a cathinone and is covered by the current Schedule 9 CATHINONES group entry. Schedule 9 recommends prohibition of manufacture, possession, supply and use, subject to approval for medical/scientific research, analytical, teaching or training purposes. The Poisons Standard is implemented through State and Territory legislation, so conduct offences and approvals are jurisdiction-specific.

N-Ethylhexedrone is the distinct cathinone 2-(ethylamino)-1-phenylhexan-1-one (C14H21NO); the Austrian legal designation is "N-Ethylhexedron". It is expressly listed in Anhang IV.1 of the current Suchtgiftverordnung as a substance of Schedule II of the UN Convention on Psychotropic Substances, making it a Suchtgift under § 2(2) SMG rather than a substance covered only as a new psychoactive substance or an analogue. The 2021 amending gazette inserted the exact designation into Anhang IV.1 with effect from 1 January 2021; the current consolidated annex still includes it. The annex's analytical/diagnostic preparation exception applies only when not used on humans or animals and the relevant controlled-substance content does not exceed 0.001%.

N-ethylhexedrone is listed by its exact name, N-ETILHEXEDRONA, in Lista F2 of Portaria SVS/MS nº 344, de 12 de maio de 1998, Anexo I, Lista F2, updated by Resolução da Diretoria Colegiada Anvisa nº 1.036, de 9 de julho de 2026, where it is also identified as 2-(ETILAMINO)-1-FENILHEXAN-1-ONA with the synonyms HEXEN and NEH; the listing has been in force since 5 June 2017. Article 4 of Portaria SVS/MS nº 344 prohibits its production, manufacture, import, export, commerce, and use, except for activities conducted by authorized bodies and institutions strictly for medical and scientific research. For personal use, article 28 of Lei nº 11.343/2006 subjects acquiring, keeping, holding in storage, transporting, or carrying it without authorization or contrary to law or regulation to a warning about the effects of drugs, community service, or an educational measure requiring attendance at a program or course.

N-Ethylhexedrone is controlled as an analogue under Schedule I, item 19 of the Controlled Drugs and Substances Act. Health Canada's Drug Analysis Service and Cannabis Laboratory classification list maps it to line 2 of that item, which covers amphetamines and their derivatives, isomers, and analogues. Unauthorized possession, trafficking, possession for trafficking, import, export, possession for export, and production are prohibited.

N-Ethylhexedrone is expressly listed by its chemical name and synonym Etilhexedrona in article 1 of Decree No. 867, the schedule for substances capable of causing dependence and grave toxic effects or considerable harm to health. The consolidated regulation identifies this as an article 1 substance under Law No. 20.000; that law criminalizes its manufacture, preparation, extraction, importation, exportation, trafficking, and related conduct absent legal authorization.

The exact structure falls under Annex 1 no. 1: the cathinone core structure is expressly included; the N-ethyl group is a permitted alkyl group of up to C6, the n-butyl substitution at the alpha carbon is a permitted alkyl group of up to C10, and the molecular mass is below 500 u. The substance is therefore a new psychoactive substance under § 2 no. 1(a), and § 3(1) no. 1 prohibits, among other things, trade, placing on the market, manufacture, importation, acquisition, possession, and administration. Exceptions apply only to recognised commercial, industrial, or scientific uses and to investigations by authorities or their appointees (§ 3(2)).

N-ethylhexedrone is prohibited in Hungary under the P2 psychotropic-substances schedule in Annex 2 of 78/2022. (XII. 28.) BM rendelet. The schedule lists it by exact name and identifies it as 2-(ethylamino)-1-phenyl-1-hexanone, with molecular formula C14H21NO and InChIKey CWNKMHIETKEBCA-UHFFFAOYSA-N. It is classified in the P2 schedule rather than the separate Annex 3 list of new psychoactive substances.

N-ethylhexedrone is controlled under SI 173/2017 Schedule 1 paragraph 1(b).

N-ethylhexedrone is expressly listed as ‘N-etilesedrone’ in Tabella I, with the chemical designation 2-(etilamino)-1-fenilesan-1-one. The 2020 decree states that it was already controlled as a 2-amino-1-phenyl-1-propanone structural analogue and specifically inserts its name in Tabella I; it enters into force fifteen days after publication and states no sunset provision. Article 73 of DPR 309/1990 applies to unauthorized conduct involving Tabella I substances; this scheduling decree creates no medicine or other substance-specific exception.

N-ethylhexedrone and its salts are listed as narcotics under Article 1, item 14 of the current consolidated designation order, which expressly names 2-(ethylamino)-1-phenylhexan-1-one and gives N-ethylhexedrone as its alternative name. The designation took effect on 7 August 2020. Article 28 of the Narcotics and Psychotropics Control Act generally prohibits possession by persons other than licensed narcotics handlers and specified facility operators, subject to statutory exceptions including possession of narcotics dispensed or supplied under a narcotics prescription.

N-Ethylhexedrone is listed expressly in the current Dutch Opiumwet List I as ‘N-ethylhexedron’, with the chemical description 2-(ethylamino)-1-fenylhexaan-1-on. Article 2 prohibits importing or exporting, preparing, processing, selling, supplying, transporting, possessing, and manufacturing a List I substance. The law provides only the statutory professional/medical and ministerial-exemption pathways, not a general possession or consumer-use exception.

Norway’s current narcotics list expressly names N-etylheksedron and identifies it as 2-(etylamino)-1-fenylheksan-1-on. Listed narcotics may be manufactured, imported, traded, supplied, or sent only to the extent expressly authorized; possession and use without lawful access are prohibited, while the statutory exceptions are authorized medical, scientific, and permitted industrial activity.

The official Polish schedule expressly identifies the chemical as HEX-EN/N-etyloheksedron and assigns it to psychotropic group I-P. Under the Anti-Drug Addiction Act, group I-P substances may be used only for research; unauthorized possession is criminalized, while the statutory research exception is subject to authorization conditions.

N-Ethylhexedrone is expressly listed by its systematic name, with the synonyms N-Ethylhexedrone and Ethyl-hexedrone, in item 16(12A) of the First Schedule's Class A drugs. It is therefore a controlled drug under the Act; possession, consumption, manufacture and trafficking are prohibited unless authorised by the Act, rather than merely covered by an analogue rule.

N-ethylhexedrone is expressly listed as N-etylnorhexedron and N-etylhexedron, with the chemical identity 2-(etylamino)-1-fenylhexan-1-on, in Förteckning I of Läkemedelsverkets föreskrifter (LVFS 2011:10) om förteckningar över narkotika. The listing took effect on 3 November 2020, and Förteckning I covers substances that normally have no medical use. Under Narkotikastrafflag (1968:64), unauthorized transfer, production for abuse, acquisition for transfer, procurement, processing, packaging, transport, storage, possession, use, sale, and offering for sale are prohibited.

Annex 5, Verzeichnis d, of the Betäubungsmittelverzeichnisverordnung (BetmVV-EDI) expressly lists N-Ethylnorhexedron and N-Ethylhexedron with the chemical identity 2-(ethylamino)-1-phenylhexan-1-one. Article 3(2)(d) of the BetmKV defines Verzeichnis d as prohibited controlled substances; cultivation, import, manufacture and placing on the market are generally forbidden. The Federal Office of Public Health may grant exceptional permits for dealings with Verzeichnis d substances for specified purposes.

N-Ethylhexedrone is controlled in the United Kingdom as a Class B drug under the Misuse of Drugs Act 1971, the relevant listing being the generic cathinone definition in Schedule 2, Part II, paragraph 1(aa), which lists any compound structurally derived from 2-amino-1-phenyl-1-propanone that is modified by phenyl-ring substitution, by an alkyl substituent at the 3-position, or by alkyl or dialkyl substitution at the nitrogen atom, other than bupropion, cathinone, diethylpropion, pyrovalerone and compounds named in sub-paragraph (a). The drug is covered by this structural family rather than by an exact-name entry: as 2-(ethylamino)-1-phenylhexan-1-one it matches the definition through an ethyl group on the nitrogen atom and an n-propyl substituent at the 3-position, and the provision has been in force since 16 April 2010 under the Misuse of Drugs Act 1971 (Amendment) Order 2010. Under section 4 of the Act it is unlawful to produce, supply or offer to supply the drug, and under section 5 it is unlawful to possess it or to possess it with intent to supply it to another, the statutory prohibitions being subject to applicable regulations and section 5 retaining its stated defences. The corresponding cathinone entry in Schedule 1 to the Misuse of Drugs Regulations 2001, paragraph 1(m), applies in England, Wales and Scotland, the amending Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2010 extending to those jurisdictions only, while the Class B provision of the 1971 Act applies throughout the United Kingdom.

Colombia's Anexo Técnico 1 expressly identifies N-ethylhexedrone as N-ETILHEXEDRONA, chemically designated 2-(etilamino)-1-fenilhexan-1-ona, in Lista Verde, Lista II. The substance is subject to fiscalización rather than categorically prohibited: the FNE control regime covers importation, exportation, processing, synthesis, manufacture, distribution, purchase, sale, and use. For substances newly added to Annex 1, Article 3 allowed a six-month application transition; after that period, no activity may be conducted until the relevant FNE or Fondo Rotatorio registration is obtained. Lista Verde II also extends control to salts and stereoisomers where chemically possible, unless expressly excepted.

N-etilhexedrona is expressly listed in List II of Annex 1 to Real Decreto 2829/1977, as amended by Orden SND/473/2021. The current consolidated text retains that listing; List II is subject to the decree's authorization and control regime rather than the blanket List I prohibition. Manufacture and traffic require authorization and registration, imports and exports require prior authorization, and unauthorized manufacture, import, export, acquisition, possession, storage, sale, supply, or distribution is classified as a very serious offence.