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Methoxypiperamide

This article is a stubmissing:
Interactions
Tolerance
Harm Potential
Legality
Methoxypiperamide molecule structureMethoxypiperamide molecule structure

Methoxypiperamide is a psychoactive drug of the piperazine class, structurally the 4-methoxy-α-keto analog of methylbenzylpiperazine. It has been sold online as a designer drug, including in combination with mephtetramine, and is reported to be inactive on its own. Very little data exists regarding its pharmacology or toxicity, though the US state of Vermont classifies it as a hallucinogen.

Dosage & Duration

Duration

After Effects1-12 hours

Subjective Effects

Legacy content. A statistically backed ontology from Mindstate Design Labs is coming soon.

This compound is reported to be inactive on its own, and no subjective effects are documented in the available material. It was sold in combination with another substance, which complicates attribution of any reported experience to this compound itself.

Reagent Testing

Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.

Liebermann(LB)
white → orange1
Marquis(MQ)
No reaction
No reaction
Mecke(ME)
No reaction
No reaction
Mandelin(MD)
No reaction
No reaction
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Pharmacology

Pharmacodynamics

Very little data exists regarding the pharmacology of methoxypiperamide. It has been reported to be inactive on its own, and was sold in combination with mephtetramine.

Pharmacokinetics

Absorption & half-lifenot documented yetMetabolitesnone documented yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Harm Potential not written up yet

History & Culture

Methoxypiperamide, also known as MeOP and MEXP, is a piperazine-class compound that appeared as a designer drug sold through online vendors. It is the 4-methoxy-α-keto analog of methylbenzylpiperazine.…

Legality

Legality not written up yet

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed — this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

Times are UTCNewest first

24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

All changes to this article · Site-wide recent changes

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