Skip to main content
Lyrea avatar

Not yet reviewed — this article is pending editorial review by Lyrea.

Citation noticeOur citation system is being overhauled

References and citation markers may currently be incomplete, mismatched, or incorrect. This system is being rebuilt and reviewed before the full site launch.

Mebroqualone

This article is a stubmissing:
Interactions
Tolerance
Harm Potential
Legality
Mebroqualone molecule structureMebroqualone molecule structure

Mebroqualone (MBQ) is a quinazolinone depressant and an analogue of mecloqualone, from which it differs by carrying a bromine atom rather than a chlorine on the 3-phenyl ring. Originally synthesized in the 1960s, it produces sedative and hypnotic effects through GABAergic activity. It is shorter-acting and more potent than methaqualone, is considered habit-forming, and appears to have circulated as a black market designer drug in Germany.

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold3-5 mg
Light5-8 mg
Moderate8-15 mg
Strong15-20 mg
Heavy20+ mg

Duration

After Effects1-4 hours

Subjective Effects

Legacy content. A statistically backed ontology from Mindstate Design Labs is coming soon.

The experience is dominated by sedation and hypnotic effects, accompanied by anxiety relief and muscle relaxation. It is described as shorter in duration and more potent than methaqualone. Memory disturbance and impaired coordination are also reported.

Physical

Sedation, hypnotic effects, muscle relaxation, and disturbed motor coordination make up the physical profile.

Cognitive

Anxiety is reduced, and amnesia is reported as a characteristic effect.

Reagent Testing

Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.

Mandelin(MD)
yellow2 → orange2 → red2 → brown2 → yellow2
Liebermann(LB)
white → yellow1
Gallic(GA)
brown1 → brown2
Morr(MO)
pink2 → green1
Powered by PROtestkit.eu

Pharmacology

Pharmacodynamics

Mebroqualone is a quinazolinone-class GABAergic that produces sedative and hypnotic effects through agonist activity at the β subtype of the GABAa receptor. It is an analogue of mecloqualone, differing by the substitution of a bromine atom for a chlorine on the 3-phenyl ring, and shares similar sedative and hypnotic properties with that parent compound. It has also been described as a shorter-acting and more potent analogue of methaqualone.

Pharmacokinetics

Absorption & half-lifenot documented yetMetabolitesnone documented yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Harm Potential not written up yet

History & Culture

Mebroqualone was originally synthesized in the 1960s as an analogue of mecloqualone, from which it differs by the substitution of a bromine atom for a chlorine on the 3-phenyl ring. Little documentation of the compound exists beyond its initial synthesis.

Legality

Legality not written up yet

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed — this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

Times are UTCNewest first

24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

All changes to this article · Site-wide recent changes

Suggest an edit

Spotted a mistake, an outdated claim, or something missing from the Mebroqualone article? Send the editors a private note. Feedback lands in a moderation queue and is never shown on the site.

Wish to give generalised feedback? You can do so here.