Not yet reviewed — this article is pending editorial review by Lyrea.
WARNINGOVERDOSE, COMBINATIONS, & WITHDRAWAL CAN BE FATAL
High doses alone or ordinary doses in combination with other depressants can fatally stop breathing. After prolonged dependency, stopping suddenly can cause seizures, delirium, or death.
Citation noticeOur citation system is being overhauled
References and citation markers may currently be incomplete, mismatched, or incorrect. This system is being rebuilt and reviewed before the full site launch.
Dosage & Duration
Dosage
Doses are population estimates that vary widely between individuals.
Dosage information for this substance remains poorly established and should be regarded as provisional.
Duration
Subjective Effects
Pharmacology
Interactions
An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.
Tolerance
Harm Potential
Addiction & Dependence
Psychological
HighClassified as habit-forming. Barbiturates as a class carry significant psychological addiction potential with regular use.
Physical
HighAs a barbiturate, hexobarbital is expected to produce physical dependence with chronic use. Barbiturate withdrawal can be severe and potentially life-threatening.
Toxicity
In severe overdose cases, coma and death can result. Specific lethal dose values are not documented in available sources.
Overdose produces progressive CNS depression including sluggishness, incoordination, difficulty thinking, slowed speech, impaired judgment, drowsiness progressing to coma, and shallow breathing.
May cause congenital abnormalities when used during pregnancy; classified as FDA Pregnancy Category D or C indicating potential teratogenic and fetotoxic effects.
History & Culture
Legality
Article Status
Step 1 · Automated synthesisAn autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.
- Step 2 · First-pass reviewPending
Not yet reviewed — this article is pending editorial review by Lyrea.
- Step 3 · Citation reviewPending
No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.
Recent changes7 human edits · latest
Times are UTCNewest first
24 January 2026
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Suggest an edit
Spotted a mistake, an outdated claim, or something missing from the Hexobarbital article? Send the editors a private note. Feedback lands in a moderation queue and is never shown on the site.
Wish to give generalised feedback? You can do so here.