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Eutylone

Eutylone molecule structureEutylone molecule structure
β-keto-1,3-benzodioxolyl-N-ethylbutanamine
bk-EBDB, N-ethylbutylone, euty

Eutylone is a synthetic psychoactive substance of the substituted cathinone and substituted phenethylamine chemical classes.citation needed It is classified as both a stimulant and an entactogen, producing a combination of effects that include increased energy and wakefulness alongside enhanced empathy and sociability. As a synthetic cathinone, eutylone belongs to a broader family of novel psychoactive substances commonly encountered in research chemical markets.

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold~50 mg
Light50-100 mg
Moderate100-150 mg
Strong150-200 mg
Heavy200+ mg

Duration

Onset15-45 minutes
Peak1-2 hours
After Effects2-6 hours
Total3-5 hours

Subjective Effects

Legacy content. A statistically backed ontology from Mindstate Design Labs is coming soon.

Eutylone produces a primarily stimulating experience with an empathogenic component that is generally described as weaker and less emotionally warm than that of MDMA, for which it has frequently been mis-sold. The effects lean heavily toward physical and mental stimulation, with the entactogenic qualities fading faster than the stimulant ones, leaving a long, wakeful tail. Compulsive redosing is commonly reported as the initial euphoria diminishes.

Physical

Physical effects are dominated by stimulation, including increased heart rate, appetite suppression, and difficulty sleeping that can persist for many hours after the primary effects have subsided.

Stimulation

Increased heart rate

Cognitive

The headspace combines mild euphoria and a muted sense of emotional openness with pronounced mental stimulation. As the experience progresses, the empathogenic warmth tends to give way to a more purely stimulated, sometimes anxious state, and users frequently report a strong urge to redose.

Emotional

Reagent Testing

Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.

Marquis(MQ)
white → yellow2
Mecke(ME)
white → yellow2 → orange2 → brown2
Mandelin(MD)
yellow2 → green3 → brown2 → brown3
Liebermann(LB)
white → yellow2 → orange2 → brown1
Powered by PROtestkit.eu

Pharmacology

Pharmacodynamics

In rat-brain synaptosome assays, eutylone inhibited uptake at DAT, NET, and SERT. It did not produce efficacious release at DAT or NET, but acted as a partial SERT releasing agent. The investigators therefore characterized eutylone as a hybrid transporter compound: an uptake inhibitor at DAT and NET with substrate-like partial releasing activity at SERT.1

These preclinical assays do not establish a human therapeutic window, safe dose, or receptor-wide binding profile.citation needed

Pharmacokinetics

No controlled human clinical pharmacokinetic study is established here. In pooled human liver microsomes and hepatocytes, eutylone showed slow in-vitro turnover: reported half-lives were 972.5 minutes in microsomes and 375.5 minutes in hepatocytes, with a predicted human hepatic extraction ratio of 0.39. These in-vitro values must not be presented as a human elimination half-life.citation needed Cross-species hepatocyte work found pronounced species differences, including much faster rat clearance, so rodent disposition should not be directly extrapolated to humans.2

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance timelines are rules of thumb, not exact schedules, and vary widely between individuals and use patterns.

Cross Tolerance

Substituted cathinones, Stimulants, Entactogens

Harm Potential

Reported adverse effects include insomnia, anxiety, tachycardia, hypertension, hyperthermia, delirium, paranoia, visual hallucinations, rhabdomyolysis, nausea, vomiting, and seizures. Severe toxicity warrants urgent medical attention.citation needed

Addiction & Dependence

Psychological

The WHO review found no animal or human studies of eutylone's dependence potential. It summarized online reports of craving and repeat dosing, but these reports are unconfirmed community evidence and should not be presented as a measured incidence of dependence.3

Toxicity

Lethal Dosage

CDC identified 343 eutylone-involved overdose deaths across 44 participating U.S. jurisdictions in 2020. Most involved other drugs: 77.3% also involved illicitly manufactured fentanyls, and 53.1% involved cocaine or methamphetamine. These surveillance data establish serious risk but do not isolate a eutylone-only lethal dose or causal contribution in each polysubstance death.citation needed Long-term human outcomes, a toxic dose threshold, and an exposure-response relationship remain unestablished in the reviewed evidence.

History & Culture

Eutylone was originally developed during the 1960s,citation needed though it remained obscure for decades before entering recreational drug markets. The compound was first reported to the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) in 2014, marking its initial appearance as a

Legality

International

Eutylone is under international control in Schedule II of the Convention on Psychotropic Substances of 1971. Commission on Narcotic Drugs Decision 65/3 placed it there in March 2022, and the scheduling change took effect on 23 November 2022. The current INCB Green List, 36th edition updated December 2025, identifies eutylone by name, IDS code PE 010, CAS number 802855-66-9 and the chemical name 1-(1,3-Benzodioxol-5-yl)-2-(ethylamino)butan-1-one. INCB's March 2026 supplement adds only MDMB-FUBINACA and does not alter eutylone's Schedule II placement. For Schedule II substances, the Convention directs Parties to limit manufacture, export, import, distribution, stocks, trade, use and possession to medical and scientific purposes and to apply licensing or similar controls. The current Yellow List, 65th edition dated July 2026, and the current Red List contain no eutylone identity match, so the applicable international designation remains psychotropic Schedule II rather than a 1961 Convention narcotic-drug schedule or a 1988 Convention precursor table. These are treaty obligations implemented by Parties, not a universal standalone domestic possession offence, so restricted_other is the applicable canonical status.

By Country

Illegal36
United States flagUnited StatesIllegal
Argentina flagArgentinaIllegal
Austria flagAustriaIllegal
Belgium flagBelgiumIllegal
Brazil flagBrazilIllegal
Canada flagCanadaIllegal (analog/blanket ban)
Chile flagChileIllegal
China flagChinaIllegal
Czech Republic flagCzech RepublicIllegal
Denmark flagDenmarkIllegal
Finland flagFinlandIllegal
France flagFranceIllegal
Germany flagGermanyIllegal
India flagIndiaIllegal
Indonesia flagIndonesiaIllegal
Ireland flagIrelandIllegal (analog/blanket ban)
Israel flagIsraelIllegal (analog/blanket ban)
Italy flagItalyIllegal
Japan flagJapanIllegal
Netherlands flagNetherlandsIllegal
New Zealand flagNew ZealandIllegal
Norway flagNorwayIllegal
Philippines flagPhilippinesIllegal
Poland flagPolandIllegal
Portugal flagPortugalIllegal
Russia flagRussiaIllegal (analog/blanket ban)
Singapore flagSingaporeIllegal
South Africa flagSouth AfricaIllegal
South Korea flagSouth KoreaIllegal (analog/blanket ban)
Sweden flagSwedenIllegal
Switzerland flagSwitzerlandIllegal
Thailand flagThailandIllegal
Turkey flagTurkeyIllegal
Ukraine flagUkraineIllegal
United Arab Emirates flagUnited Arab EmiratesIllegal
United Kingdom flagUnited KingdomIllegal (analog/blanket ban)
Controlled / restricted4
Australia flagAustraliaRestricted
Colombia flagColombiaRestricted
Mexico flagMexicoRestricted
Spain flagSpainRestricted

References

Source Pages

  1. Bluelight: Eutylone discussion thread
  2. Bluelight: Eutylone mis-sold as MDMA
  3. Erowid Experience Reports: Eutylone (bk-EBDB)
  4. Erowid: Sweet Little Stim (ID 114422)
  5. Erowid: Very Nice but Habit Forming (ID 115241)
  6. IsomerDesign: Eutylone Status Report
  7. PsychonautWiki Talk: Eutylone
  8. Wikipedia

Citations

  1. Eutylone and Its Structural Isomers Interact with Monoamine Transporters and Induce Locomotor Stimulation. ACS Chemical Neuroscience, 12(7), 1170–1177 (April 2021). https://doi.org/10.1021/acschemneuro.0c007971
  2. Cross-species metabolic characterization of eutylone and mechanism-based inhibition of CYP2D6 and CYP2B6 with drug interaction implications. pmc.ncbi.nlm.nih.gov (n.d.). https://doi.org/10.1038/s41598-026-48814-712
  3. World Health Organization Expert Committee on Drug Dependence. cdn.who.int (n.d.). https://cdn.who.int/media/docs/default-source/essential-medicines/unedited-advance-copy-44th-ecdd-critical-review-report-eutylone.pdf12
  4. Notes From the Field: Overdose Deaths Involving Eutylone (Psychoactive Bath Salts) — United States, 2020. (n.d.). https://www.cdc.gov/mmwr/volumes/71/wr/mm7132a3.htm1
  5. ANMAT Disposition No. 3943/2026 under Psychotropics Law No. 19,303. argentina.gob.ar (n.d.). https://www.argentina.gob.ar/normativa/nacional/norma-427110/texto1
  6. ANMAT Disposition No. 3943/2026 under Psychotropics Law No. 19,303. argentina.gob.ar (n.d.). https://www.argentina.gob.ar/sites/default/files/anexo_i_ecn.pdf1
  7. Customs (Prohibited Imports) Regulations 1956, Schedule 4 item 90B; Customs (Prohibited Exports) Regulations 1958, Schedule 8 item 12B. legislation.gov.au (n.d.). https://www.legislation.gov.au/F1996B03651/2026-07-13/2026-07-13/text/original/epub/OEBPS/document_1/document_1.html1
  8. Customs (Prohibited Imports) Regulations 1956, Schedule 4 item 90B; Customs (Prohibited Exports) Regulations 1958, Schedule 8 item 12B. legislation.gov.au (n.d.). https://www.legislation.gov.au/F1996B03403/2026-01-22/2026-01-22/text/original/pdf1
  9. Suchtgiftverordnung, Anlage IV. ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/GeltendeFassung.wxe?ShowPrintPreview=True&abfrage=bundesnormen&gesetzesnummer=100110531
  10. Suchtgiftverordnung, Anlage IV. ris.bka.gv.at (n.d.). https://www.ris.bka.gv.at/Dokumente/BgblAuth/BGBLA_2024_II_6/BGBLA_2024_II_6.html1

Further Reading

  1. CDC: Overdose Deaths Involving Eutylone 2020
  2. DrugWise: Eutylone

Article Status

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    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

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  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

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24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

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