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bk-2c-B
bk-2C-B is a psychedelic substance of the phenethylamine class and a β-keto derivative of 2C-B. Richard Glennon and colleagues first reported it in the scientific literature in 2004, and it later appeared as a novel designer drug on European markets in 2013. While it did not generate significant excitement upon its appearance, it remained consistently available and was sampled by a relatively large number of users. The drug is administered orally.
Dosage & Duration
Dosage
Doses are population estimates that vary widely between individuals.
Threshold~80 mg
Light80-150 mg
Moderate150-500 mg
Strong500-1000 mg
Heavy1000+ mg
Individual responses to this substance vary considerably. Oral bioavailability is significantly reduced when the compound is dissolved in water; using gel capsules or wrapping the material in cigarette paper and consuming it with an acidic drink improves absorption. The intranasal route is generally poorly tolerated.
Duration
Onset20-70 minutes
Total10-40 hours
Subjective Effects
Legacy content. A statistically backed ontology from Mindstate Design Labs is coming soon.
Effects vary widely by individual, dose, and context.
Physical
Cognitive
Visual
Hallucinatory States
Auditory
See also: Psychedelic Intensity Scale, Effects of psychedelics (visual, cognitive, miscellaneous)
Pharmacology
Pharmacodynamics
bk-2C-B acts as a serotonin 5-HT2A receptor agonist with very low potency. It is the β-keto derivative of 2C-B.
Pharmacokinetics
Absorption & half-lifenot documented yetMetabolitesnone documented yet
Interactions
Interactions not written up yet
An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.
Tolerance
Tolerance not written up yet
Harm Potential
Toxicity
Lethal Dosage
The extracted material describes highly variable reported doses and long duration, but gives no toxic or lethal dose.
central nervous system
A user report describes mental fatigue, psychedelic stimulation, and increasing difficulty hiding intoxication.
musculoskeletal/physical
The user report describes body strain and high body load.
ocular/autonomic
Dilated pupils were observed in the user report.
History & Culture
bk-2C-B was first characterized in the scientific literature in 2004 by pharmacologist Richard Glennon and his research team, who synthesized and studied the compound as part of investigations into phenethylamine structure-activity relationships. The substance remained largely obscure until 2013,…
Legality
By Country
Illegal3
CanadaIllegalIn Canada, bk-2C-B is controlled under Schedule III, item 35, of the Controlled Drugs and Substances Act. Its structure falls within the item’s generic definition of 2C-phenethylamines, which encompasses the compound’s bromine ring substituent and beta-carbon oxo group; bk-2C-B is not listed there by name. Since 31 October 2016, unauthorized possession, trafficking, possession for trafficking, import, export, possession for export, and production have been prohibited.
GermanyIllegal (analog/blanket ban)bk-2C-B is covered in Germany by the generic structural definition for 2-phenethylamine-derived compounds in Anlage 1 Nr. 1 of the NpSG. Its structure falls within the permitted bromine and methoxy ring substitutions and beta-keto derivatives, and its molecular mass is below the 500 u ceiling. The NpSG prohibits trade, placing on the market, manufacture, import, export, transit, acquisition, possession and administration to another person, subject to its statutory exclusions and exemptions. Simple acquisition or possession is prohibited but is not itself one of the basic criminal acts listed in § 4(1).
United KingdomIllegal (analog/blanket ban)In the United Kingdom, bk-2C-B falls under the Psychoactive Substances Act 2016 when it is capable of producing the Act's defined psychoactive effect and is not exempted. Subject to the relevant purpose and mental-state elements, the Act prohibits production, supply or offers to supply, possession with intent to supply, import, and export for psychoactive consumption. It does not create a general simple-possession offence outside a custodial institution, although possession for intended psychoactive consumption in a custodial institution is prohibited. For offences under sections 4 to 8, conviction on indictment carries up to seven years' imprisonment, a fine, or both.
Controlled / restricted1
SwitzerlandRestrictedIn Switzerland, bk-2C-B has been expressly listed since 1 December 2014 in Annex 6, List e, no. 137 of the BetmVV-EDI, a category for materials and products suspected of narcotic-like effects. List e substances are subject to the control measures applicable to List a narcotics, but the designation is distinct from List d for prohibited substances. Cultivation, manufacture, import, export, storage, use, or placing bk-2C-B on the market requires authorization from the Federal Department of Home Affairs; unauthorized conduct is punishable by up to three years’ imprisonment or a monetary penalty.
References
Citations
- PubChem PUG REST — CID 11288812 synonyms. pubchem.ncbi.nlm.nih.gov (n.d.). https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/11288812/synonyms/JSON12
- PubChem PUG REST, CID 11288812 compound properties. pubchem.ncbi.nlm.nih.gov (n.d.). https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/11288812/property/IUPACName,MolecularFormula,ConnectivitySMILES/JSON1
- Controlled Drugs and Substances Act, current consolidated Schedule III. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/section-sched95602.html1
- Controlled Drugs and Substances Act, section 4. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/section-4.html1
- Controlled Drugs and Substances Act, section 5. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/section-5.html1
- Controlled Drugs and Substances Act, section 6. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/section-6.html1
- Controlled Drugs and Substances Act, section 7. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/acts/C-38.8/section-7.html1
- Order Amending Schedule III to the Controlled Drugs and Substances Act (2C-phenethylamines), SOR/2016-73. gazette.gc.ca (n.d.). https://gazette.gc.ca/rp-pr/p2/2016/2016-05-04/html/sor-dors73-eng.html1
- Controlled Drugs and Substances Act, archived Schedule III effective 2016-10-31. laws-lois.justice.gc.ca (n.d.). https://www.laws-lois.justice.gc.ca/eng/acts/C-38.8/section-sched95602-20161031.html1
- PubChem PUG REST — CID 11288812 compound properties. pubchem.ncbi.nlm.nih.gov (n.d.). https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/11288812/property/IUPACName,MolecularFormula,MolecularWeight,CanonicalSMILES/JSON1
Article Status
Step 1 · Automated synthesisAn autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.
- Step 2 · First-pass reviewPending
Not yet reviewed — this article is pending editorial review by Lyrea.
- Step 3 · Citation reviewPending
No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.
Recent changes7 human edits · latest
Times are UTCNewest first
24 January 2026
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
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