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Amfecloral

This article is a stubmissing:
Subjective Effects
Pharmacology
Interactions
Tolerance
History & Culture
Legality
Amfecloral molecule structureAmfecloral molecule structure
N-(2,2,2-trichloroethylidene)amphetamine
Amphecloral, Acutran
Psychoactive Class
StimulantDepressantSedative
Chemical Class
Amphetamine (substituted)

Dosage & Duration

Duration

Onset10-30 minutes
After Effects1-12 hours
Total5-8 hours

Subjective Effects

Subjective Effects not written up yet

Pharmacology

Pharmacology not written up yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

High

As a prodrug to amphetamine, amfecloral carries significant psychological addiction potential consistent with the amphetamine class, including risk of compulsive use and difficulty discontinuing.

Physical

Moderate

Physical dependence may develop with regular use due to its dual action as a prodrug to both amphetamine and chloral hydrate, with potential for withdrawal symptoms from both stimulant and sedative components.

History & Culture

History & Culture not written up yet

Legality

Legality not written up yet

References

Source Pages

  1. TripSit Factsheet: Amfecloral
  2. Wikipedia

Further Reading

  1. Amfecloral product monograph ‘Acutran’ (Parke-Davis, 1969 archival brochure).
  2. Fitch FW et al. Anorectic drugs: comparative appraisal. American Journal of Clinical Nutrition (1970)
  3. Ganellin CR, Triggle DJ. Dictionary of pharmacological agents (1996)
  4. McPherson EM. Pharmaceutical Manufacturing Encyclopedia, 3rd Edition (2007)
  5. PubChem: Amfecloral compound overview
  6. Van Rossum JM. Mode of action of psychomotor stimulant drugs. International Review of Neurobiology (1970)

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed — this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

Times are UTCNewest first

24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

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