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Alpha-GPC
Dosage & Duration
Dosage
Doses are population estimates that vary widely between individuals.
Duration
Subjective Effects
Pharmacology
Interactions
An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.
Tolerance
Harm Potential
Addiction & Dependence
Psychological
Higher doses may increase adverse effects, including possible addiction-related concerns, but Alpha-GPC-specific addiction risk has not been characterized.
Toxicity
A large retrospective cohort study associated alpha-GPC use with higher stroke risk, though a later meta-analysis criticized the statistics.
Headaches are listed among physical side effects.
Teeth grinding is listed among physical side effects.
Body odor alteration may occur in susceptible populations, especially people with trimethylaminuria.
History & Culture
Legality
By Country
CanadaLegal (regulated)
United StatesNot scheduledReferences
Source Pages
Citations
- Product information — NPN 80084798 (Elevate). health-products.canada.ca (n.d.). https://health-products.canada.ca/lnhpd-bdpsnh/info?licence=800847981
- Natural Health Products Regulations (SOR/2003-196), section 4. laws-lois.justice.gc.ca (n.d.). https://laws-lois.justice.gc.ca/eng/regulations/sor-2003-196/section-4.html1
- Licensed Natural Health Products Database (LNHPD). canada.ca (n.d.). https://www.canada.ca/en/health-canada/services/drugs-health-products/natural-non-prescription/applications-submissions/product-licensing/licensed-natural-health-products-database.html1
- Controlled Substances — Alphabetical Order. deadiversion.usdoj.gov (n.d.). https://www.deadiversion.usdoj.gov/schedules/orangebook/c_cs_alpha.pdf1
- GRN No. 419 — L-alpha-glycerylphosphorylcholine. hfpappexternal.fda.gov (n.d.). https://www.hfpappexternal.fda.gov/scripts/fdcc/index.cfm?id=419&set=grasnotices1
- Submitted 75-Day Premarket Notifications for New Dietary Ingredients, 1995 to Present. fda.gov (n.d.). https://www.fda.gov/media/193536/download?attachment=1
Further Reading
Article Status
Step 1 · Automated synthesisAn autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.
- Step 2 · First-pass reviewPending
Not yet reviewed — this article is pending editorial review by Lyrea.
- Step 3 · Citation reviewPending
No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.
Recent changes7 human edits · latest
Times are UTCNewest first
24 January 2026
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
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