WARNINGDANGER OF DEATH
High doses alone or ordinary doses in combination with other depressants can fatally stop breathing.
Citation noticeOur citation system is being overhauled
References and citation markers may currently be incomplete, mismatched, or incorrect. This system is being rebuilt and reviewed before the full site launch.
4-MeO-Butyrfentanyl
4-MeO-Butyrfentanyl is a rare synthetic opioid and analogue of fentanyl, distinct from the related compound butyrfentanyl. It is classified as a research chemical with habit-forming properties. Extremely limited information exists regarding its pharmacology, safety profile, and appropriate dosing parameters. As with other fentanyl analogues, overdose carries a significant risk of respiratory depression. Extreme caution is strongly advised, and it should not be combined with other stimulants or depressants.
Dosage & Duration
Dosage
Doses are population estimates that vary widely between individuals.
Reliable dosage data for this compound remains extremely scarce, and any figures should be treated with considerable caution.
Duration
Subjective Effects
Pharmacology
Interactions
An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.
Tolerance
Harm Potential
Addiction & Dependence
Psychological
Classified as habit-forming. Very limited information is available due to the rarity of this substance.
Toxicity
As an opioid, overdose may result in respiratory depression.
History & Culture
4-MeO-Butyrfentanyl is a rare synthetic opioid belonging to the fentanyl analogue class of compounds. The substance has received minimal documentation in both scientific literature and online harm reduction communities, and its precise history of synthesis and development remains poorly documented. It should be distinguished from the related compound butyrfentanyl, which has been more extensively characterized.
Legality
Article Status
Step 1 · Automated synthesisAn autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.
- Step 2 · First-pass reviewPending
Not yet reviewed — this article is pending editorial review by Lyrea.
- Step 3 · Citation reviewPending
No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.
Recent changes7 human edits · latest
Times are UTCNewest first
24 January 2026
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more
Suggest an edit
Spotted a mistake, an outdated claim, or something missing from the 4-MeO-Butyrfentanyl article? Send the editors a private note. Feedback lands in a moderation queue and is never shown on the site.
Wish to give generalised feedback? You can do so here.