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4-CBC

This article is a stubmissing:
Subjective Effects
Pharmacology
Interactions
Tolerance
History & Culture
Legality
4-CBC molecule structure4-CBC molecule structure
4-Chlorobuphedrone
Psychoactive Class
StimulantEntactogen (mild)
Chemical Class
Cathinone (substituted)

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold~40 mg
Light40-70 mg
Moderate50-80 mg
Strong80-100 mg
Heavy100+ mg

Subjective Effects

Subjective Effects not written up yet

Reagent Testing

Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.

Mandelin(MD)
yellow2 → brown2
Liebermann(LB)
white → yellow1
Simons(SI)
orange1 → black2 → blue1 → blue2
Zimm(ZI)
white → white1 → yellow1
Powered by PROtestkit.eu

Pharmacology

Pharmacology not written up yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Toxicity

Central Nervous System

This substance is considered potentially very neurotoxic, though no scientific reports have formally characterized this risk; extreme caution is advised.

Cardiovascular

Potential cardiotoxicity has been flagged as a concern, though no scientific reports have formally documented cardiac effects.

History & Culture

History & Culture not written up yet

Legality

Legality not written up yet

References

Further Reading

  1. Andrzejczak D et al. Case series of 4-CBC intoxications in Poland, 2019
  2. EMCDDA Europol Early-Warning Report: 4-Chlorobuphedrone
  3. EMCDDA: 4-Chlorobuphedrone En
  4. Grifell M et al. Patterns of use and toxicity of new para-halogenated substituted cathinones
  5. Grigoryev A et al. Identification and analytical characterization of 4-chlorobuphedrone
  6. Jamey C et al. Pharmacological profile of halogenated cathinones including 4-CBC

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed — this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

Recent changes7 human edits · latest

Times are UTCNewest first

24 January 2026

  1. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  2. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  3. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  4. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  5. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  6. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

  7. Josie Kins · Updated the article · also 1,4-Butanediol, 1B-LSD, 1cP-AL-LAD and 573 more

All changes to this article · Site-wide recent changes

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